Results 241 to 250 of about 216,445 (311)

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Prehospital aspirin use is associated with improved clinical outcomes in pulmonary embolism: A retrospective case-control study. [PDF]

World J Cardiol
Suresh MG, Mohamed S, Shanmugavel Geetha H, Sekar A, Prabhu S, Sargent J, Abraham GM, Hatwal J, Batta A, Mohan B.   +9 more
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Aspirin for Secondary Prevention: Are Patients Getting Wiser Than Their Physicians? [PDF]

JACC Adv
Cleland JG, Clark AL.
europepmc   +1 more source

Lattice Strain and Piezoelectric Field Modulated Piezo‐Photocatalytic Nitrate‐to‐Ammonia Conversion in Chemically Bonded S‐Scheme Heterojunction

Advanced Science, EarlyView.
Under ultrasonic excitation, 5% compressive strain optimizes the ZnO@ZnSe heterojunction. The strain enhances H2O dissociation into active *H on Zn sites and NO3− adsorption on Se sites, facilitating their hydrogenation into NH4+ with optimal kinetics and thermodynamics. Abstract Piezo‐photocatalysis provides an efficient approach to harness mechanical
Shuo Liu, Jing Li, Zhiwei Liu, Jiaxuan Song, Huijun Lv, Dongdong Xiao, Qizhao Wang, Yongzheng Zhang, Qikun Xue   +8 more
wiley   +1 more source

Study protocol for low-dose evaluation of aspirin in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention (LEAST): a multicenter, double-blind, randomized controlled clinical trial. [PDF]

Ann Med
Zheng W, Gong ZT, Qian HY.
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Aspirin, cardiovascular events, and major bleeding in older adults: extended follow-up of the ASPREE trial. [PDF]

Eur Heart J
Wolfe R, Broder JC, Zhou Z, Murray AM, Ryan J, Chan AT, Nelson MR, Woods RL, Ernst ME, Orchard SG, Kirpach B, Reid CM, Shah RC, Stocks N, Margolis KL, Neumann JT, Wilson M, Fitzgerald S, Mahady SE, Wood EM, Ket S, Eaton CB, Hand P, Malik M, Abhayaratna WP, Venkataraman P, Chan P, Cloud GC, Donnan GA, Williamson JD, Tonkin AM.   +30 more
europepmc   +1 more source

Heterointerface‐Functionalized Photoelectric Response of Metal‐Oxide Schottky Photodiode for Intelligent Fire Detection

Advanced Science, EarlyView.
A heterointerface‐functionalized Schottky photodiode (HF‐SPD) is developed to explore the photoelectric capabilities of low‐temperature oxide semiconductors. Besides the remarkable UV detection capability, the bias‐tunable photo response endows HF‐SPD with the unique wavelength selectivity.
Yuyang Cai, Zhiwei Zheng, Zhiwu Zhong, Yuhan Zhang, Tengyan Huang, Yucheng Cao, Dawei Zheng, Yen Hung Lin, Fion Sze Yan Yeung, Kuan‐Chang Chang, Jie Chen, Hoi Sing Kwok, Lei LU, Yufeng Jin   +13 more
wiley   +1 more source

The Extended Safety and Efficacy of Indobufen in Conjunction With P2Y12 Receptor Inhibitors Among Patients Undergoing Revascularization: A Meta-Analysis and Overview. [PDF]

Cardiovasc Ther
Yi M, Cao Q, Sheng YH, Wu L, Ke X.
europepmc   +1 more source