Results 81 to 90 of about 447,619 (420)
BMC Research Notes, 2011 Background Guidelines recommend an early initiation of aspirin treatment in patients with acute cerebral ischemia. Comparative studies on the best starting dose for initiating aspirin therapy to achieve a rapid antiplatelet effect do not exist.
Overbeck Ursula +3 more
doaj +1 more source
2H-NMR studies of supercooled and glassy aspirin [PDF]
Journal of Non-Crystalline Solids, 353, 3788 (2007), 2007 Acetyl salicylic acid, deuterated at the methyl group, was investigated using 2H-NMR in its supercooled and glassy states. Just above the glass transition temperature the molecular reorientations were studied using stimulated-echo spectroscopy and demonstrated a large degree of similarity with other glass formers.
arxiv +1 more source
Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence [PDF]
Sci Rep 11, 23179 (2021), 2020 Amid the pandemic of 2019 novel coronavirus disease (COVID-19) infected by SARS-CoV-2, a vast amount of drug research for prevention and treatment has been quickly conducted, but these efforts have been unsuccessful thus far. Our objective is to prioritize repurposable drugs using a drug repurposing pipeline that systematically integrates multiple SARS-
arxiv +1 more source
Cognitive Impairment and Age-Related Vision Disorders: Their Possible Relationship and the Evaluation of the Use of Aspirin and Statins in a 65 Years-and-Over Sardinian Population [PDF]
, 2014 Neurological disorders (Alzheimer’s disease, vascular and mixed dementia) and visual loss (cataract, age-related macular degeneration, glaucoma, and diabetic retinopathy) are among the most common conditions that afflict people of at least 65 years of ...
Caminiti G +13 more
core +1 more source
Polypill with or without Aspirin in Persons without Cardiovascular Disease.
New England Journal of Medicine, 2020 BACKGROUND A polypill comprising statins, multiple blood-pressure-lowering drugs, and aspirin has been proposed to reduce the risk of cardiovascular disease.
S. Yusuf +20 more
semanticscholar +1 more source
Effect of aspirin in "aspirin sensitive" patients. [PDF]
BMJ, 1984 Eighteen patients with a history of urticaria or asthma, or both, induced by aspirin were studied before and after provocation of symptoms with aspirin. The plasma prostaglandin F2 alpha concentration, which was characteristically raised before challenge, fell significantly at the time of adverse reactions.
A W Frankland +4 more
openaire +3 more sources
Excited state dynamics of some nonsteroidal anti-inflammatory drugs: a surface-hopping investigation [PDF]
, 2019 Here we present a computational investigation of the excited state dynamics of 5 different active medical substances (aspirin, ibuprofen, carprofen, suprofen, indomethacin) which belong to the family of nonsteroidal anti-inflammatory drugs (NSAIDs). The nonadiabatic dynamics simulations were performed using the surface hopping method, with electronic ...
arxiv +1 more source
The encapsulation of hydrophobic drugs in Pluronic F127 micelles: the effects of drug hydrophobicity, solution temperature and pH [PDF]
Langmuir, 29, 4350 (2013), 2014 Three drugs, Ibuprofen, Aspirin and Erythromycin, are encapsulated in spherical Pluronic F127 micelles. The shapes and the size distributions of the micelles in dilute, aqueous solutions, with and without drugs, are ascertained using cryo- Scanning Electron Microscopy and Dynamic Light Scattering (DLS) experiments, respectively. Uptake of drugs above a
arxiv +1 more source
Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer : a systematic review and overview of reviews [PDF]
, 2013 Background: Prophylactic aspirin has been considered to be beneficial in reducing the risks of heart disease and cancer. However, potential benefits must be balanced against the possible harm from side effects, such as bleeding and gastrointestinal (GI ...
Clarke, Aileen +9 more
core +1 more source
Archives of Neurology, 1990 In our recent article, 1 we reviewed the available evidence on aspirin and other antiplatelet agents in the secondary and primary prevention of cardiovascular disease. We concluded that low-dose aspirin should be a possible adjunct, not an alternative, to coronary risk factor management and, in view of its possible side effects, should be prescribed ...
Buring, J +4 more
openaire +3 more sources