Results 151 to 160 of about 88,625 (333)

Impact of pharmacogenetics on aspirin resistance: a systematic review. [PDF]

Arq Neuropsiquiatr, 2023
Silva GFD, Lopes BM, Moser V, Ferreira LE.   +3 more
europepmc   +1 more source

Aspirin Resistance in Diabetic Patients [PDF]

, 2004
Michele Sacco, Fabio Pellegrini, Maria Carla Roncaglioni, Fausto Avanzini, Gianni Tognoni, Antonio Nicolucci   +5 more
openalex   +1 more source

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

Advanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni, He Chen, Qiaqi Chen, Yangyang Liao, Yunqian Wang, Linyan Ye, Xiaohui Wu, Hongyu Ni, Tingyun Jiang, Shufen Li, Qiong Yang, Hong Xue, Zhongju Wang, Feng Yi, Cunyou Zhao   +14 more
wiley   +1 more source

Aspirin Resistance in Obese and Elderly Patients with COVID-19? [PDF]

Am J Med, 2021
Chiang KC, Gupta A.
europepmc   +1 more source

Aspirin resistance: Table 1 [PDF]

, 2004
Graeme J. Hankey, John W. Eikelboom
openalex   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Molecular Design of Difluorinated Polyether Electrolyte for Ultrastable High‐Voltage All‐Solid‐State Lithium Metal Batteries

Advanced Science, EarlyView.
This work develops an in situ polymerized difluorinated polyether electrolytes (DPEs) for all‐solid‐state lithium metal batteries (ASSLMBs). The DPE exhibits superior interfacial stability and ion conductivity, due to the synergistic electron‐withdrawing and ion solvation effects of difluorinated functional groups.
Zhenyao Wei, Yufeng Luo, Yongqiang Yang, Yaxin Tang, Junhua Zhou, Chao Luo, Ruo Wang, Huipeng Zeng, Chaoyang Wang, Xiaoxiong Xu, Yonghong Deng, Zijian Zheng, Jian Chang   +12 more
wiley   +1 more source

EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib‐Resistant Lung Cancer Therapy

Advanced Science, EarlyView.
In this study, an EGFR lipoSM PROTACs (GM‐protac), which can achieve efficient EGFR degradation and HDACi delivery, is developed. It is found that GM‐protac can both block EGFR‐dependent pathways and bypass the HDAC signaling pathway. Meanwhile, both display obvious tumor inhibition with negligible toxicity in EGFR‐TKI‐resistant lung cancer animal ...
Dongyuan Wang, Yajing Liu, Ying Chen, Chuan Dai, Wenzhu Hu, Jinyan Han, Zigang Li, Feng Yin, Yu Zhang, Chen Shi   +9 more
wiley   +1 more source

O/C Ratio‐Driven Fluorescence Enhancement in Cellulose‐Derived Carbon Quantum Dots: Mechanistic Insights into Reaction Pathways

Advanced Science, EarlyView.
Three types of CQDs are prepared from cellulose and its derivatives via hydrothermal carbonization. An increase in the atomic O/C ratio from 0.25 to 0.61 results in a nearly seven‐fold enhancement in QY. DFT calculations verify this mechanism. Further, this study elucidates the formation pathways of cellulose‐derived CQDs and proposes a fluorescence ...
Yarong Shi, Siyu Zhao, Xiheng Kang, Xinrui Chen, Xue Ou, Meng Nan Chong, Xueping Song, Zhanying Zhang   +7 more
wiley   +1 more source

Enhanced Single‐Particle Upconversion Imaging via Energy Migration Boosting

Advanced Science, EarlyView.
A core‐shell‐shell Yb3⁺/Er3⁺ UCNP architecture is engineered to balance energy migration and back energy transfer, yielding more than a tenfold enhancement in single‐particle brightness. Leveraging these optimized probes, it achieves long‐term, high‐resolution single‐particle tracking in live neurons, uncovering coordinated transport mechanisms of ...
Yanxin Zhang, Rongrong Wen, Tianli Zhai, Wenrui Zhang, Fan Ding, Huan Ling, Yunxiang Zhang, Qian Liu   +7 more
wiley   +1 more source