Results 181 to 190 of about 47,972 (292)

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

open access: yesAdvanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin   +11 more
wiley   +1 more source

Aspirin resistance and diabetes mellitus [PDF]

open access: bronze, 2008
Ramzi Ajjan   +2 more
openalex   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

open access: yesAdvanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao   +10 more
wiley   +1 more source

Personalized Neoantigen Vaccine plus Regorafenib Increases Rgs2⁺CD8⁺ T Cells Infiltration and Reprograms the Tumor Microenvironment in Microsatellite Stable Colorectal Cancer Liver Metastases

open access: yesAdvanced Science, EarlyView.
This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen   +11 more
wiley   +1 more source

A Self‐Powered Double U‐Finger MME Resonator Capable of Wirelessly Capturing Abnormal Message in Smart Grid Networks

open access: yesAdvanced Science, EarlyView.
This study presents a magneto‐mechano‐electric resonator that efficiently harvests energy and monitors grid safety in Power Internet of Things systems. The resonator, consisting of two U‐fingers with different resonant frequencies, captures stray magnetic field energy and detects fault messages. It produces high power for self‐powered and achieves high
Xinyi Zheng   +10 more
wiley   +1 more source

Resveratrol Inhibits Aggregation of Platelets from High-risk Cardiac Patients with Aspirin Resistance

open access: bronze, 2006
Gyorgyi Stef   +4 more
openalex   +1 more source

Perioperative management of aspirin resistance after off‐pump coronary artery bypass grafting: possible role for aprotinin [PDF]

open access: bronze, 2008
Robert Poston   +9 more
openalex   +1 more source

Molecular Design of Difluorinated Polyether Electrolyte for Ultrastable High‐Voltage All‐Solid‐State Lithium Metal Batteries

open access: yesAdvanced Science, EarlyView.
This work develops an in situ polymerized difluorinated polyether electrolytes (DPEs) for all‐solid‐state lithium metal batteries (ASSLMBs). The DPE exhibits superior interfacial stability and ion conductivity, due to the synergistic electron‐withdrawing and ion solvation effects of difluorinated functional groups.
Zhenyao Wei   +12 more
wiley   +1 more source

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