Results 231 to 240 of about 3,875,152 (312)

Oleuropein and punicic acid induce oxidative stress and cytotoxicity in MCF-7 breast cancer cells, with protection by peroxiredoxin antioxidant proteins. [PDF]

Mol Biol Rep
Diiorio S, Quitmeyer B, Phelan SA.
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Development of the Tunneled Agar Plate Assay (TAPA) for Microbial Co-culture Screening of Antibacterial Activity against Pathogenic Bacteria. [PDF]

J Microbiol Biotechnol
Shin G, Kim H, Kim Y, Lee J, Kang J, Yun E, Song T, Ha S, Hur J, Lee H, Kang S, Kim C, Choi S, Park J, Kim G, Lee J.   +15 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Updated Hepatitis D Seroprevalence Among Hepatitis B Surface Antigen-Positive Persons Aged ≥6 Years in the United States, National Health and Nutrition Examination Survey, 2007‒2018. [PDF]

Clin Infect Dis
Casillas SM, Chida A, Drobeniuc J, Sandul AL, Kamili S, Jiles RB, Thomas DL, Tobian AAR, Patel EU, Teshale EH.   +9 more
europepmc   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Factor VIII Aurora: a naturally occurring gain-of-function FVIII variant with enhanced FIXa affinity. [PDF]

Blood
Morris JJ, Davidson RJ, Watson CT, George LA.   +3 more
europepmc   +1 more source

Diagnostic performance of a loop-mediated isothermal amplification test for the diagnosis of human and cat sporotrichosis in two highly endemic areas in Brazil: insights from a real-world, field-based evaluation. [PDF]

Braz J Microbiol
Almeida-Paes R, Munhoz LS, Mendoza SR, Poester VR, de Souza Rabello VB, Schirmer H, Custódio MGF, Mattevi VS, Freitas DFS, Xavier MO, Zancopé-Oliveira RM, Severo CB.   +11 more
europepmc   +1 more source

Development and qualification of quantitative assays for detecting process-related nucleic acid impurities in recombinant AAV preparations. [PDF]

Mol Ther Adv
Janc M, Dobnik D.
europepmc   +1 more source

Modulation of Antitumor Immunity and the Tumor Microenvironment by <i>Scutellaria barbata</i> D. Don: A Scoping Review and Network Pharmacology Analysis. [PDF]

Int J Mol Sci
Kim SD, Park JH, Kim DH, Yeo T, Choi MJ, Park SJ, Yoo HS.   +6 more
europepmc   +1 more source