KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Machining quality and efficiency are vital for the high-performance assembly of high strength CFRTP components. Strain rate sensitivity of thermoplastic matrix results in complex machining mechanism under the wide range of cutting speed.
Kuangqing Hu +4 more
doaj +1 more source
Decision on the Support of a Draft Resolution at the Sixty Sixth Ordinary Session of the General Assembly of the United Nations to Ban Female Genital Mutilation in the World Doc. Assembly/Au/12(Xvii) Add.5 [PDF]
Burkina Faso for a resolution to be adopted at the Sixty Sixth Ordinary Session of the General Assembly of the United Nations to ban female genital Mutilation (FGM) in the ...
The Assembly
core
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Decision on the “Reconsideration of Decision Assembly/Au/Dec.263(Xiii) on the Transformation of the African Union Commission into the African Union Authority” Doc. Assembly/Au/17(Xv) Add.10 [PDF]
“Reconsideration of Decision Assembly/AU/Dec.263 (XIII) on the Transformation of the African Union Commission into the African Union ...
The Assembly
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
This book contains reports from the national officers and program directors of The Links, Inc., about the activities of the national level of the organization from 1978-1980. It was presented to the 24th National Assembly.
Links, Inc. National Assembly.
core
Decision on the Implementation of the Previous Decisions of the Executive Council and the Assembly Doc. Ex.Cl/623(Xviii) [PDF]
Decision on the Implementation of the previous decisions of the executive council and the assembly - Doc.
The Assembly
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Arkansas Delphian Assembly scrapbook
This collection contains a scrapbook documenting the activities of the Arkansas Delphian Assembly from 1931 to ...
Arkansas Delphian Assembly
core

