Decision on the Date and Venue of the Twenty-Third Ordinary Session of the Assembly of the African Union [PDF]
Twenty-third Ordinary Session of Assembly of the African Union scheduled for July 2014 in Libreville ...
The Assembly
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Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Decision on the Implementation of the Previous Decisions of the Executive Council and the Assembly Doc. Ex.Cl/581(Xvii) [PDF]
Report of the Commission on the Implementation of the Previous Decisions of the Executive Council and the Assembly of the African ...
The Assembly
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
This book contains reports from the national officers and program directors of The Links, Inc., about the activities of the national level of the organization from 1984-1986. It was presented to the 25th National Assembly.
Links, Inc. National Assembly.
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Decision on the Offer of the Great Socialist People’s Libyan Arab Jamahiriya to Host the Twenty First Ordinary Session of the Assembly of the Union, June/July 2013 Doc. Assembly/Au/15(Xvi) Add.1 [PDF]
Great Socialist People's Libyan Arab Jamahiriya to host the Twenty First Ordinary Session of the Assembly of the African Union in June/July ...
The Assembly
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Primaries and General Assembly districts
Title from Web page (publisher's Web site, viewed Mar. 15, 2011).; "February 9, 1995."; Discusses the number of General Assembly districts that are single-town and multi-town districts.
Janicki, Mary M.
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Decision on the report of the 7th Ordinary Meeting of the Specialized Technical Committee on Defence, Safety and Security of the African Union Doc. Assembly/AU/4(XXII) [PDF]
Decision [Assembly/AU/Dec.489(XXI ...
The Assembly
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