Results 41 to 50 of about 4,209,255 (350)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Assembly, remodelled

open access: yeseLife, 2013
Biochemical assays reveal that nucleosome maturation and chromatin remodelling by the motor protein Chd1 are distinct, separable enzymatic activities.
Bouazoune, Karim, Kingston, Robert
openaire   +4 more sources

Concept and implementation of an agent-based control architecture for a cyber-physical assembly system

open access: yesMATEC Web of Conferences, 2016
Today’s production companies are challenged with: the assembly of different product variants with lot size of one on a single assembly line and the increase of product variants.
Müller Rainer   +4 more
doaj   +1 more source

A Product Development Approach in The Field of Micro-Assembly with Emphasis on Conceptual Design

open access: yesApplied Sciences, 2019
Faster product lifecycles make long-term investments in machines for micro assembly riskier. Therefore, reconfigurable manufacturing systems gain more and more attention.
Christoph Gielisch   +3 more
doaj   +1 more source

Constraints on Assembly Bias from Galaxy Clustering

open access: yes, 2016
We constrain the newly-introduced decorated Halo Occupation Distribution (HOD) model using SDSS DR7 measurements of projected galaxy clustering or r-band luminosity threshold samples.
Bosch, Frank C. van den   +4 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila

open access: yesNature Communications, 2018
Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription ...
Holger Apitz, Iris Salecker
doaj   +1 more source

Multi-objective topology optimization and structural analysis of periodic spaceframe structures

open access: yesMaterials & Design, 2020
Reduction of structural weight provides significant benefits in many engineering applications. While methods to optimise structural shape and topology of both continuous solids and discrete frame structures have existed for a while, the advent of ...
Jarad Lim, Chao You, Iman Dayyani
doaj   +1 more source

RIOT: a simple graphical assembly tool [PDF]

open access: yes, 1982
Errors in the chip assembly process are harder to find than errors in cell design, since they belong to no specific part of the design, but rather to the assembly as a whole. Assembly errors are more costly than call design errors also, since they often
Rowson, Jim, Trimberger, Stephen
core  

The Interfacial-Organized Monolayer Water Hindering the Aggregation of Nanographene: Both in Stacking and Sliding Assembly Pathways

open access: yes, 2012
A computational investigation was carried out to understand the aggregation of nanoscale graphene with two typical assembly pathways of stacking assembly and sliding assembly in water.
Lv, Wenping, Wu, Renan
core   +1 more source

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