Results 81 to 90 of about 131,326 (303)
A methodology for the concurrent design of products and their assembly sequence [PDF]
, 1999 This thesis reports on the development of a Two-Tier methodology that provides support for assembly sequence construction, validation and evaluation in parallel with the design.
Barnes, C. J.
core
Using Apache Spark on genome assembly for scalable overlap-graph reduction
Human Genomics, 2019 Background De novo genome assembly is a technique that builds the genome of a specimen using overlaps of genomic fragments without additional work with reference sequence.
Alexander J. Paul +5 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Visualisation and analysis of RNA-Seq assembly graphs [PDF]
Nucleic Acids Research, 2018 Abstract RNA-sequencing (RNA-Seq) is a powerful transcriptome profiling technology enabling transcript discovery and quantification. RNA-Seq data are large, and most commonly used as a source of genelevel quantification measurements, whilst the underlying assemblies of reads, if inspected, are usually viewed as sequence reads mapped on ...
Fahmi W Nazarie +12 more
openaire +8 more sources
Virtual bloXing - assembly rapid prototyping for near net shapes [PDF]
, 2009 Virtual reality (VR) provides another dimension to many engineering applications. Its immersive and interactive nature allows an intuitive approach to study both cognitive activities and performance evaluation.
Corney, Jonathan +6 more
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Assembly graph visualization [PDF]
Digital assembly instructions can help Users better assemble a product but creating them can be a time-consuming task and often only show one assembly path.
Graef, Jannik
core +1 more source
Computing the graph-based parallel complexity of gene assembly [PDF]
, 2010 We consider a graph-theoretical formalization of the process of gene assembly in ciliates introduced in Ehrenfeucht et al. (2003) [3], where a gene is modeled as a signed graph.
Alhazov, Artiom, Petre, Ion, Li, Chang
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
A graph-based approach to diploid genome assembly [PDF]
Bioinformatics, 2018 Abstract Motivation Constructing high-quality haplotype-resolved de novo assemblies of diploid genomes is important for revealing the full extent of structural variation and its role in health and disease. Current assembly approaches often collapse the two sequences into one haploid consensus sequence
Shilpa Garg +5 more
openaire +3 more sources
Graph kernel extensions and experiments with application to molecule classification, lead hopping and multiple targets [PDF]
, 2009 The discovery of drugs that can effectively treat disease and alleviate pain is one of the core challenges facing modern medicine. The tools and techniques of machine learning have perhaps the greatest potential to provide a fast and efficient route ...
Demco, Anthony A, Demco, Anthony A.
core