Results 51 to 60 of about 7,311 (216)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Faba Bean–Oat Mixtures Modify Rhizosphere Microbiota and Nutrient–Biomass Regulation on the Qinghai–Tibetan Plateau

Agronomy
Grass–legume mixtures are increasingly recognized for their potential to enhance soil health and forage productivity through belowground biotic interactions. In this study, we evaluated the effects of Vicia faba L. (faba bean 4060)–Avena sativa L.
Huilin Yan, Xin Jin, Panda Ye, Changcai Teng, Yujiao Liu   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Distribution patterns of soil bacteria, fungi, and protists emerge from distinct assembly processes across subcommunities

Ecology and Evolution
Environmental change exerts a profound effect on soil microbial domains—including bacteria, fungi, and protists—that each perform vital ecological processes.
Alexis Kayiranga, Alain Isabwe, Haifeng Yao, Huayuan Shangguan, Justin Louis Kafana Coulibaly, Martin Breed, Xin Sun   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Shifts in Structure and Assembly Processes of Root Endophytic Community Caused by Climate Warming and Precipitation Increase in Alpine Grassland

Microorganisms
Climate change poses great challenges to the survival of plants. Plant endophytes play important roles in improving plant adaptability. However, our knowledge of the effects of climate change on endophytic community structures is limited.
Xiaoting Wei, Bing Han, Jinxin Zhang, Xinqing Shao   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Temperate Forest Soil Microbiomes and Their Assembly Processes are Modulated by the Interplay of Co‐Existing Tree Species Identity, Diversity and Their Mycorrhizal Type

Journal of Sustainable Agriculture and Environment
Recent studies have highlighted the significant role of tree species' mycorrhizal traits on forest soil microbial communities and their associated ecosystem functions.
Hafeez Ul Haq, Bala Singavarapu, Amelie Hauer, Nico Eisenhauer, Olga Ferlian, Helge Bruelheide, Tesfaye Wubet   +6 more
doaj   +1 more source