Results 101 to 110 of about 7,216,108 (304)

METHODOLOGY FOR ASSESSING THE NATURAL BLOCK OF TOURIST AND RECREATIONAL POTENTIAL OF THE STUDIED TERRITORIES [PDF]

open access: yesGeo Journal of Tourism and Geosites
The purpose of the study is to create and approbation of the author's methodology for assessing the tourism and recreational potential of components included in the natural block, on the example of the Republic of Mordovia and North Kazakhstan region ...
Pavel S. DMITRIYEV   +6 more
doaj   +1 more source

Assessment and feedback to students

open access: yes, 2011
This is one of ten resource units developed and released by the CPD4HE project. The resources support the professional development of HE teachers. They are aimed particularly at staff working towards HEA accreditation but are available to anyone who may ...
Dr Rosalind Duhs
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

2024 Assessment Seminar

open access: yes
Worksheet template and a sample of a completed worksheet that walks through the assessment cycle.
Byrne, Sephra
core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Methodology for Assessing the Level of Greenhouse Gas Emissions in Agricultural Crops Production

open access: yesСельскохозяйственные машины и технологии
The global rise in average environmental temperatures is associated with the emission of greenhouse gases due to human economic activities, including crop production.
N. I. Dzhabborov   +3 more
doaj   +1 more source

Addendum Report: Environmental Assessment of the Sludge Handling Facilities Proposed by the Township of Wayne

open access: yes, 1974
This report is an addendum to a previous report, "Environmental Assessment of the Expansion of the Mountain View Sewerage Treatment Facilities, Wayne Township, New Jersey," of May 11, 1973.

core   +1 more source

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