Results 81 to 90 of about 7,216,108 (304)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Report on Statistical Disclosure Limitation Methodology [PDF]
Originally Prepared by Subcommittee on Disclosure Limitation Methodology 1994; Revised by Confidentiality and Data Access Committee 2005The Federal Committee on Statistical Methodology (FCSM) was organized by the Office of Management and Budget (OMB) in ...
United States. Federal Committee on Statistical Methodology
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Ekonomika Nauki, 2015 There had been reviewed a subject coverage and citation rating of Russian scientific-periodical journals, indexed in Web of Science Core Collection. It was demonstrated that out of 223 scientific subject areas, identified by the classifier Web of Science
O. A. Yeremchenko, L. A. Tsvetkova
doaj
Assessing the knowledge index of the region
Вестник Российского экономического университета имени Г. В. Плеханова, 2019 Economy of knowledge is an economic formation, where today’s generation of young people will work. It is quite good that many scientists try to forecast what it will be like.
S. N. Kukushkin
doaj +1 more source
Pilot of adaptive comparative judgement within Sociology: full report
, 2014 Report on a pilot project commissioned by College Development Network (CDN) to investigate the potential for the use of an innovative assessment methodology called Comparative Judgement in the delivery of coursework and essay assessment as part of the ...
TAG Assessment
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Risk assessment methodology for the forniture industrial sector
, 2014 Companies need to constantly make decisions about risk. They need to decide if a certain risk level is low enough or if some measures for its reduction are still needed.
Rodrigues, Matilde A.
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source