An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Multi-criteria decision making with linguistic labels: a comparison of two methodologies applied to energy planning [PDF]
This paper compares two multi-criteria decision making (MCDM) approaches based on linguistic label assessment. The first approach consists of a modified fuzzy TOPSIS methodology introduced by Kaya and Kahraman in 2011. The second approach, introduced by
Afsordegan, Arayeh +4 more
core
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Underlying dimensions of knowledge assessment : factor analysis of the knowledge assessment methodology data [PDF]
The Knowledge Assessment Methodology (KAM) database measures variables that may be used to assess the readiness of countries for the knowledge economy and has many policy uses.
Chen, Derek H. C., Gawande, Kishore
core
The 1996 research assessment exercise : the library and information management panel [PDF]
Reports on the 1996 Research Assessment Exercise (RAE), the fourth such exercise aimed at providing funding councils of UK universities (including former polytechnics) with the necessary data to rate the quality of UK academic research for predetermined ...
CJ Houghton +7 more
core +4 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
POLICY FOR THE ASSESSMENT AND COMPENSATION OF DAMAGES FROM THE RUSSIAN FEDERATION’S AGGRESSION AGAINST UKRAINE [PDF]
The military aggression of the Russian Federation against Ukraine has led to significant destruction and economic losses, which must be compensated.
Valerii Zhuk +3 more
doaj +1 more source
Preliminary comparative assessment of land use for the Satellite Power System (SPS) and alternative electric energy technologies [PDF]
A preliminary comparative assessment of land use for the satellite power system (SPS), other solar technologies, and alternative electric energy technologies was conducted. The alternative technologies are coal gasification/combined-cycle, coal fluidized-
Newsom, D. E., Wolsko, T.
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

