Results 121 to 130 of about 1,602,944 (312)
Development and inter-rater reliability of the Liverpool adverse drug reaction causality assessment tool. [PDF]
, 2011 To develop and test a new adverse drug reaction (ADR) causality assessment tool (CAT)
Smyth, RL +8 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Research progress on symptom assessment tools for endocrine therapy in breast cancer patients
Huli yanjiu, 2020 This paper reviewed the symptom assessment tools for endocrine therapy in breast cancer patients in China and abroad，and pointed out that the currently assessment tools were lack of specificity，comprehensiveness and accuracy.On the basis of the existing ...
LI Qingqing, WU Wanying
doaj
, 2011 The work described in this paper relates to the development and use of a range of initiatives in order to mark complex masters' level assignments related to the development of computer web applications.
Barker, Trevor, Bennett, Steve
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Research status quo of health literacy related assessment tools for patients with chronic diseases
Huli yanjiu, 2015 AbstractIt reviewed the general health literacy assessment scale and the health literacy assessment scale of specific chronic disease patients，and put forward the evaluation dimensions of existing some scale were still not comprehensive and needed to be ...
潘丽娟, 张明, 安力彬
doaj
Research progress on symptom cluster management of lymphoma patients
Huli yanjiu, 2020 This article reviewed the research progress on symptom cluster management of lymphoma patients from the manifestations，evaluation tools，and intervention status of lymphoma patients，and intended to provide references for clinical evaluation and ...
CUI Panpan +3 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Predicting the likelihood of non-healing : a venous leg ulcer risk assessment tool
, 2014 This project developed, validated and tested reliability of a risk assessment tool to predict the risk of failure to heal of patients with venous leg ulcers within 24 weeks. The risk assessment tool will allow clinicians to be able to determine realistic
Parker, Christina Narelle
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