Results 131 to 140 of about 3,507,817 (309)
Increasing Use of Risk Assessment at Release in The Continuing Leverage of Paroling Authorities: Findings from a National Survey [PDF]
, 2016 The Parole Release and Revocation Project launched a national survey of paroling authorities across the United States in 2015. Preliminary results from the survey has allowed the Parole Project team to examine changing and current practices regarding how
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Developing a Performance Assessment System From the Ground Up: Lessons Learned From Three Linked Learning Pathways [PDF]
, 2014 This document is designed to offer practitioners -- teachers, principals, and central office administrators -- models, tools, and examples from the Linked Learning field for developing a performance assessment system.
Ann Jaquith +2 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Huli yanjiu, 2018 Early identification and management of emotional and social dysfunction in stroke patients was crucial.Choosing appropriate screening tools to evaluate stroke patients and adopting targeted interventions could speed up the recovery of neurological ...
He Qingwen, Duan Gongxiang
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Towards a model for evaluating student learning via e-assessment
, 2010 The need for practical tools to assess student learning at the course level is becoming a more pressing goal for all academic institutions. This is because learning assessment tools which monitor both student performance and conceptual change events that
Hench, Thomas, Whitelock, Denise
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