Results 131 to 140 of about 1,218,698 (310)

Research progress on quality of life in patients with age related macular degeneration

open access: yesHuli yanjiu, 2016
It introduced the assessment tools and status quo of quality of life,and influencing factors of patients with age related macular degeneration.It prompted that the quality of life of patients with aged related macular degeneration was affected by central
Li Shu, Cheng Yun
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developing Poverty Assessment Tools Based on Principal Component Analysis: Results from Bangladesh, Kazakhstan, Uganda, and Peru

open access: yes
Developing accurate, yet operational poverty assessment tools to target the poorest households remains a challenge for applied policy research. This paper aims to develop poverty assessment tools for four countries: Bangladesh, Peru, Uganda, and ...
Zeller, Manfred   +4 more
core  

Research progress on the concept and application of comprehensive geriatric assessment for the elderly

open access: yesHuli yanjiu, 2023
LI Wanling   +5 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Support for Gender Equality Among Men Scale: Adaptation to Turkish culture

open access: yes
Men's participation is an important indicator for achieving gender equality. The purpose of this study is to adapt the “Support for Gender Equality among Men Scale (SGEMS)” developed by Sudkamper et al. (2020) to Turkish. The scale examines men'
Daşcı, Esra   +3 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Using Visual Tools for Analysis and Learning

open access: yes, 2010
This pack is intended as a resource for lecturers and students to facilitate the further development of their learning and teaching strategies. Visual tools were initially introduced within a module of the Year 3 nursing curriculum within the University ...
Burton, Rob   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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