Results 101 to 110 of about 1,037,455 (301)
Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
Health shock, medical insurance and financial asset allocation: evidence from CHFS in China. [PDF]
Health Econ Rev, 2022 Liu Y, Hao Y, Lu ZN.
europepmc +1 more source
Asset Allocation and Asset Location: Household Evidence from the Survey of Consumer Finances [PDF]
The rapid growth of assets in self-directed tax-deferred retirement accounts has generated a new set of financial decisions for many households. In addition to deciding which assets to hold, households with substantial assets in both taxable and tax ...
Daniel Bergstresser, James Poterba
core
Advanced Science, EarlyView.ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo +16 more
wiley +1 more source
Optimal Asset Allocation with Factor Models for Large Portfolios [PDF]
This paper characterizes the asymptotic behaviour, as the number of assets gets arbitrarily large, of the portfolio weights for the class of tangency portfolios belonging to the Markowitz paradigm.
M. Hashem Pesaran, Paolo Zaffaroni
core
Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
Digital inclusive finance and asset allocation of Chinese residents: Evidence from the China Household Finance Survey. [PDF]
PLoS One, 2022 Li K, Mengmeng H, Huo J.
europepmc +1 more source
Empirical Evaluation of Investor Rationality in the Asset Allocation Puzzle [PDF]
We examine the portfolio-choice puzzle posed by Canner, Mankiw, and Weil (1997). The idea is to test a conclusion reached by Elton and Gruber (2000), stating that a bonds/stocks ratio which decreases in relation to risk tolerance does not necessarily ...
Georges Dionne +2 more
core
Advanced Science, EarlyView.ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su +4 more
wiley +1 more source
Can VAR models capture regime shifts in asset returns? a long-horizon strategic asset allocation perspective [PDF]
In the empirical portfolio choice literature it is often invoked that through the choice of predictors that may closely track business cycle conditions and market sentiment, simple Vector Autoregressive (VAR) models could produce optimal strategic ...
Stuart Hyde, Massimo Guidolin
core