Results 61 to 70 of about 2,109,388 (295)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Abstract Analysis and Revision Assignment Using MS Word Readability Statistics

open access: yesPrompt, 2018
In teaching technical writing for nearly 20 years, I have recognized the importance of including writing assignments focused on improving students' clarity and effectiveness at the sentence level.
Julie Dyke Ford
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Beginning Mathematical Writing Assignments

open access: yesPrompt, 2019
Writing assignments in any mathematics course always present several challenges, particularly in lower-level classes where the students are not expecting to write more than a few words at a time.
Alexander Halperin   +2 more
doaj   +1 more source

From STRs to SNPs via ddRAD‐seq: Geographic assignment of confiscated tortoises at reduced costs

open access: yesEvolutionary Applications, 2022
Assigning individuals to their source populations is crucial for conservation research, especially for endangered species threatened by illegal trade and translocations.
Roberto Biello   +9 more
doaj   +1 more source

Multi-sided Böhm-Bawerk assignment markets: the core [PDF]

open access: yes, 2013
[cat] En aquest treball introduïm la classe de "multi-sided Böhm-Bawerk assignment games", que generalitza la coneguda classe de jocs d’assignació de Böhm-Bawerk bilaterals a situacions amb un nombre arbitrari de sectors.
Tejada, Oriol
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

5′-Oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione

open access: yesMolbank
The structure verification of 5′-oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione by NMR is reported. Toward this aim, 2D NMR techniques including 1H-1H COSY, HMQC, and HMBC experiments were used to assist with the assignment of the 1H and 13C chemical ...
Dimitar Stoitsov   +4 more
doaj   +1 more source

The opinion podcast: A visceral form of persuasion

open access: yesPrompt, 2020
In this assignment, students create a podcast episode in which they make an argument on a topic in current events. Through this process, students develop traditional rhetorical skills such as awareness of audience, formulation of a thesis, and inclusion ...
Alison Klein
doaj   +1 more source

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