Results 61 to 70 of about 710,280 (318)

Abstract Analysis and Revision Assignment Using MS Word Readability Statistics

open access: yesPrompt, 2018
In teaching technical writing for nearly 20 years, I have recognized the importance of including writing assignments focused on improving students' clarity and effectiveness at the sentence level.
Julie Dyke Ford
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Beginning Mathematical Writing Assignments

open access: yesPrompt, 2019
Writing assignments in any mathematics course always present several challenges, particularly in lower-level classes where the students are not expecting to write more than a few words at a time.
Alexander Halperin   +2 more
doaj   +1 more source

From STRs to SNPs via ddRAD‐seq: Geographic assignment of confiscated tortoises at reduced costs

open access: yesEvolutionary Applications, 2022
Assigning individuals to their source populations is crucial for conservation research, especially for endangered species threatened by illegal trade and translocations.
Roberto Biello   +9 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

5′-Oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione

open access: yesMolbank
The structure verification of 5′-oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione by NMR is reported. Toward this aim, 2D NMR techniques including 1H-1H COSY, HMQC, and HMBC experiments were used to assist with the assignment of the 1H and 13C chemical ...
Dimitar Stoitsov   +4 more
doaj   +1 more source

The opinion podcast: A visceral form of persuasion

open access: yesPrompt, 2020
In this assignment, students create a podcast episode in which they make an argument on a topic in current events. Through this process, students develop traditional rhetorical skills such as awareness of audience, formulation of a thesis, and inclusion ...
Alison Klein
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Automated Chemical Shift Assignments of MAS Solid-State NMR Spectra of Complex Protein Systems by ssPINE/ssPINE-POKY

open access: yesApplied Sciences
Solid-state nuclear magnetic resonance (ssNMR) spectroscopy enables studying complex macromolecules with low solubility. Compared to solution NMR, few tools exist for biomacromolecule ssNMR data analysis.
Andrea Estefania Lopez Giraldo   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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