Results 71 to 80 of about 840,099 (248)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Complements and substitutes in multilateral assignment markets [PDF]
I prove that, in assignment markets with more than two sides, agents of different sides (or sectors) need not be complements, whereas agents of the same side need not be substitutes.
Oriol Tejada
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
On the dimension of the core of the assignment game [PDF]
The set of optimal matchings in the assignment matrix allows to define a reflexive and symmetric binary relation on each side of the market, the equal-partner binary relation.
Marina Nunez Oliva +1 more
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Robust pole assignment techniques via state feedback [PDF]
, 2000 We present a unifying computational framework to solve robust pole assignment problems for linear systems using state feedback. The new framework uses Sylvester equation based parametrizations of the pole assignment problems.
Varga, Andras
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Processes for understanding sustainability as a goal and practice
Journal of Geography, Politics and Society, 2017 The concept of sustainability has become one of today’s most widely used and controversial concepts. It is therefore important to develop activities within organizational context in order to increase co-workers understanding of the goals for more ...
Anette Oxenswärdh
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Literary Analysis Assignment [Composition] [PDF]
, 2018 This assignment was used in English 102 Writing through Literature course and was designed to meet LaGuardia’s Inquiry and Problem Solving Core Competency and Written Communication Ability. Students were expected to critically reflect on issues-- such as
Chatterji, Tuli
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