Results 91 to 100 of about 840,099 (248)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Fen ve Teknoloji Dersinde Verilen Ödevlerin Öğrenci Görüşlerine Göre Değerlendirilmesi

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2009
Bu çalışma, ilköğretim okullarının II. kademesindeki öğrencilerin Fen ve Teknoloji derslerinde verilen ev ödevlerine ilişkin görüşlerini değerlendirmek amacıyla yapılmıştır. Araştırmada, survey tarama yöntemi kullanılmıştır.
Caner Aladağ, Süleyman Doğu
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Multi-sided Bohm-Bawerk assignment markets: the core [PDF]

open access: yes
We introduce the class of multi-sided B ohm-Bawerk assignment games, which generalizes the well-kown two-sided B ohm-Bawerk assignment games to situations with an arbitrary number of sectors. We reach the extreme core allocations of any multi-sided B ohm-
Oriol Tejada
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Assignment submarkets with a segment core [PDF]

open access: yes
The Böhm-Bawerk horse markets are assignment markets with homogeneous goods that are known to have a one-dimensional core. We show here that, although there exist two-sided assignment games with non-homogeneous products and with a segment as a core, the
Marina Nunez, Carles Rafels
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Assign construction tasks among group of workers with respect to minimizing total work risk on the base of DOISIS-MODEL

open access: yesSalāmat-i kār-i Īrān, 2017
Background and aims: Evaluation of physical pressure during different working conditions is one of the important and applicable aspects of human factors engineering at industrial and construction environments.
hamed salmanzadeh, ali mohammad maysami
doaj  

The extreme core allocations of the assignment game [PDF]

open access: yes
Although assignment games are hardly ever convex, in this paper a characterization of their set or extreme points of the core is provided, which is also valid for the class of convex games.
Marina Nunez Oliva   +1 more
core  

Robust pole assignment for descriptor systems [PDF]

open access: yes, 2000
By using a generalized Sylvester equation based parametrization, three minimum norm robust pole assignment problems for descriptor systems are formulated as unconstrained minimization problems for suitably chosen cost functions.
Varga, Andras
core  

Home - About - Disclaimer - Privacy