Results 91 to 100 of about 710,280 (318)

Robust pole assignment techniques via state feedback

open access: yes, 2000
We present a unifying computational framework to solve robust pole assignment problems for linear systems using state feedback. The new framework uses Sylvester equation based parametrizations of the pole assignment problems.
Varga, Andras
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Assignment submarkets with a segment core [PDF]

open access: yes
The Böhm-Bawerk horse markets are assignment markets with homogeneous goods that are known to have a one-dimensional core. We show here that, although there exist two-sided assignment games with non-homogeneous products and with a segment as a core, the
Marina Nunez, Carles Rafels
core  

Complex Mixture Analysis of Organic Compounds in Yogurt by NMR Spectroscopy

open access: yesMetabolites, 2016
NMR measurements do not require separation and chemical modification of samples and therefore rapidly and directly provide non-targeted information on chemical components in complex mixtures.
Yi Lu   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Culminating Wiki Assignment

open access: yes, 2021
Culminating Wiki Assignment to use digital writing in an asynchronous class ...
Cruz, Deirdre
core  

Flipped Classroom Activity Using the PTA Model in an Introductory Sociology Course

open access: yesPrompt, 2018
This scaffolded writing-to-learn activity incorporates a number of Writing Across the Curriculum-based suggestions that draw upon the strengths of student reflection, the PTA (prioritization, translation, and analogization) model of concentric thinking ...
Lauren M. Sardi
doaj   +1 more source

Assignment Problems [PDF]

open access: yesThe Computer Journal, 1964
J. S. Clowes, Ewan S. Page
openaire   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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