Results 81 to 90 of about 710,280 (318)
Informational Interview Assignment Prompt
An assignment that asks students to interview a person of their ...
Crowe, Brenna E.
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Intentions and Assignments [PDF]
The aim of this work is propose a logical approach to intention dynamics based on the notion of assignment [3, 7]. The function of an assignment is to associate the truth value of a certain formula ϕ to a propositional atom p. We combine a static modal logic of belief and choice with three kinds of dynamic modalities and corresponding three kinds of ...
Lorini, E +4 more
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The assignment game: core bounds for mixed-pair coalitions
In the assignment game framework, we try to identify those assignment matrices in which no entry can be increased without changing the coreof the game.
Rafels, Carles +1 more
core
Processes for understanding sustainability as a goal and practice
The concept of sustainability has become one of today’s most widely used and controversial concepts. It is therefore important to develop activities within organizational context in order to increase co-workers understanding of the goals for more ...
Anette Oxenswärdh
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

