Results 91 to 100 of about 189,524 (323)

Her Choice, Her Problem: How Having a Choice Can Diminish Family Solidarity [PDF]

open access: yes, 2011
This Article explores a little-noticed dimension of abortion and assisted suicide (or voluntary euthanasia): how choosing to reject those options can have a negative impact on the legally authorized choosers.
Stith, Richard
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

A Legislation Review: Bill C-14 “Euthanasia or Assisted Dying” [PDF]

open access: yes, 2017
This article is a policy analysis that covers the request for an amendment for the doctor assisted suicide law introduced as BillC-14 on June 16, 2016, exploring the considerations to further expand the bill to better meet individual’s rights regarding ...
Stewart, Kullen G
core   +1 more source

Rights of passage: law and the biopolitics of dying [PDF]

open access: yes, 2009
Deleuze and Law: Forensic Futures explores the relation between law and life and the advent of a politics of 'life'. How have recent events focused social, political and cultural attention on the living body and its maintenance and management?
A Cavarero   +7 more
core   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Involvement of palliative care in euthanasia practice in a context of legalized euthanasia : a population-based mortality follow-back study [PDF]

open access: yes, 2017
Background: In the international debate about assisted dying, it is commonly stated that euthanasia is incompatible with palliative care. In Belgium, where euthanasia was legalized in 2002, the Federation for Palliative Care Flanders has endorsed the ...
Chambaere, Kenneth   +3 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

The power of suggestion

open access: yesMedicine Anthropology Theory, 2019
This article examines an ethical controversy that has received relatively little attention in public debates about the legalization of medical aid-in-dying (AID): should physicians inform patients that they have the option of hastening death?
Mara Buchbinder
doaj   +1 more source

Referral for medical assistance in dying [PDF]

open access: yesCanadian Medical Association Journal, 2018
Excellent article.[1][1] It seems to me that the College of Physicians and Surgeons of Ontario is trying to bully and force physicians to endorse an ideology with the threat of job loss, calling it a patient access issue.
openaire   +3 more sources

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