Results 131 to 140 of about 502,954 (343)

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities [PDF]

open access: yes, 2014
STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight or obese women are smaller than those from women of healthy weight, yet post-fertilization ...
Leary, C.   +5 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Recent advances in bird sperm morphometric analysis and its role in male gamete characterization and reproduction technologies

open access: yesAsian Journal of Andrology, 2016
Postcopulatory sexual selection through sperm competition may be an important evolutionary force affecting many reproductive traits, including sperm morphometrics.
Julian Santiago-Moreno   +8 more
doaj   +1 more source

The curse of Frankenstein: visions of technology and society in the debate over new reproductive technologies [PDF]

open access: yes, 2003
At each successive moment in their development new reproductive technologies have provided the occasion for virulent argument about the role of technology in human affairs. And more generally, technoscientific knowledge has long been held both in awe and
Bloomfield, B P, Vurdubakis, T
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ovarian teratoma in the mare: a review and two cases [PDF]

open access: yes, 2010
A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart   +10 more
core  

The attitudes of infertile couples towards assisted reproductive techniques in Yazd, Iran: A cross sectional study in 2014

open access: yesInternational Journal of Reproductive BioMedicine, 2016
Background: Knowledge about assisted reproductive techniques (ART) and its procedures affect the attitude of infertile people. Making decisions about the use of ART is affected by one's perception and attitude.
S. Afshani   +4 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Assisted reproductive techniques in the prevention of mitochondrial diseases

open access: yesUniversidad Médica Pinareña, 2020
Introduction: the mitochondrion is an important organelle that has its own DNA that is sensitive to mutations. These mutations can cause mitochondrial diseases, a heterogeneous group that suggests mitochondrial dysfunction.
Felipe De Jesús López-Catá   +2 more
doaj   +2 more sources

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