Results 61 to 70 of about 318,953 (318)

Deficiency of RARα Suppresses Decidualization via Downregulating CEBPB Transcription in Women With Recurrent Implantation Failure

Frontiers in Endocrinology, 2022
BackgroundRecurrent implantation failure (RIF) is a disease associated with endometrial receptivity dysfunction. Retinoic acid receptor alpha (RARα) is an important protein in many biological processes, such as differentiation and development.
Caiyi Huang, Caiyi Huang, Caiyi Huang, Caiyi Huang, Caiyi Huang, Qian Zhang, Qian Zhang, Qian Zhang, Tianxiang Ni, Tianxiang Ni, Tianxiang Ni, Tingting Zhou, Tingting Zhou, Tingting Zhou, Chunzi Lv, Chunzi Lv, Chunzi Lv, Yan Li, Yan Li, Yan Li, Junhao Yan, Junhao Yan, Junhao Yan, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen   +27 more
doaj   +1 more source

Long-term health of children conceived after assisted reproductive technology

Upsala Journal of Medical Sciences, 2020
The aim of this narrative review is to summarize the present knowledge on long-term outcome of children born after assisted reproductive technologies (ART).
C. Bergh, U. Wennerholm
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Effect of SARS-CoV-2 infection on human embryonic development and clinical outcomes: a retrospective cohort study

BMC Pregnancy and Childbirth
Objective To investigate the effect of SARS-CoV-2 infection on embryonic development and clinical outcomes. Methods This retrospective analysis included 538 couples in December 2022.
Li Tian, Yiting Sun, Miaomiao Jia
doaj   +1 more source

Status of racial disparities between black and white women undergoing assisted reproductive technology in the US

Reproductive Biology and Endocrinology, 2020
Background Numerous studies have demonstrated substantial differences in assisted reproductive technology outcomes between black non-Hispanic and white non-Hispanic women. We sought to determine if disparities in assisted reproductive technology outcomes
D. Seifer, B. Simsek, E. Wantman, A. Kotlyar   +3 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Growth Hormone Promotes in vitro Maturation of Human Oocytes

Frontiers in Endocrinology, 2019
Increasing the success rate of in vitro maturation (IVM) for human oocytes has a major clinical significance. Previous studies have shown that growth hormone (GH) added into IVM medium could promote IVM of oocytes from non-human beings.
Yue Li, Yue Li, Yue Li, Hui Liu, Hui Liu, Hui Liu, Qingqing Yu, Qingqing Yu, Qingqing Yu, Hongbin Liu, Hongbin Liu, Hongbin Liu, Tao Huang, Tao Huang, Tao Huang, Shigang Zhao, Shigang Zhao, Shigang Zhao, Jinlong Ma, Jinlong Ma, Jinlong Ma, Han Zhao, Han Zhao, Han Zhao   +23 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Transcriptional insights on the incomplete cytoplasmic maturation and developmental potential of oocytes cultured without granulosa cells in mice

BMC Genomics
Background Oocyte maturation is crucial for female fertility and embryonic development, encompassing nuclear and cytoplasmic maturation. Supportive cells of follicles, such as granulosa cells, are essential for oocyte growth and maturation.
Yibo Wang, Yichuan Zhang, Tianjie Li, Yun Ren, Ping Zhou, Lin Fu, Chenxi Xiao, Ziying Huang, Hanji Huang, Wenfeng Xie, Yuxin Luo, Yanan Qi, Hongcui Zhao, Yang Yu, Yong Fan, Heng Pan   +15 more
doaj   +1 more source