Results 51 to 60 of about 9,404,323 (308)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Transcriptional insights on the incomplete cytoplasmic maturation and developmental potential of oocytes cultured without granulosa cells in mice

open access: yesBMC Genomics
Background Oocyte maturation is crucial for female fertility and embryonic development, encompassing nuclear and cytoplasmic maturation. Supportive cells of follicles, such as granulosa cells, are essential for oocyte growth and maturation.
Yibo Wang   +15 more
doaj   +1 more source

Influencing of serum inflammatory factors on IVF/ICSI outcomes among PCOS patients with different BMI

open access: yesFrontiers in Endocrinology, 2023
IntroductionOverweight and obese are important factors leading to the occurrence of long-term complications in women with polycystic ovary syndrome (PCOS).
Yilei He   +31 more
doaj   +1 more source

`Human clones talk about their lives': Media representations of assisted reproductive and biogenetic technologies [PDF]

open access: yes, 2007
This article examines New Zealand print media representations of assisted reproductive and related biogenetic technologies, conceptualized as the products of a concordance of interest between media workers and reproductive specialists, biogenetic ...
Michelle, Carolyn
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Efficacy and safety of mesenchymal stem cell therapy for ovarian ageing in a mouse model

open access: yesStem Cell Research & Therapy
Background Ovarian ageing is one of the major issues that impacts female fertility. Mesenchymal stem cell (MSC)-based therapy has made impressive progress in recent years.
Wendi Pei   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Direct warming and rehydration method in frozen embryo transfer: study protocol for a pragmatic, multi-center, double-blinded, two-arm randomized controlled trial

open access: yesTrials
Background Embryo cryopreservation through vitrification is widely used to store surplus embryos for future transfer. Traditional multi-step warming methods are both time-consuming and costly.
Waner Wu   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Growth Hormone Promotes in vitro Maturation of Human Oocytes

open access: yesFrontiers in Endocrinology, 2019
Increasing the success rate of in vitro maturation (IVM) for human oocytes has a major clinical significance. Previous studies have shown that growth hormone (GH) added into IVM medium could promote IVM of oocytes from non-human beings.
Yue Li   +23 more
doaj   +1 more source

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