Safety issues in assisted reproduction technology: The children of assisted reproduction confront the responsible conduct of assisted reproductive technologies [PDF]
Human Reproduction, 2002 Neurological sequelae and multiple birth defects have been observed in children conceived by IVF and ICSI. Multiple pregnancy is the most important risk factor. These health problems challenge the responsible practice of medicine. The core values of medicine and the deontology of the profession have been reviewed to define the responsible conduct of ...
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Assisted reproductive technology in Europe 2007 : results generated from European registers by ESHRE [PDF]
, 2012 Peer ...
Nygren, K G +14 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Trials, 2018 Background Obese women have fewer oocytes retrieved, an increased cancelation rate, a higher miscarriage rate, and a lower live birth rate after assisted reproductive technology (ART) treatment compared with women with normal weight.
Jing Li +7 more
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‘What are you going to do, confiscate their passports?’ Professional perspectives on cross-border reproductive travel [PDF]
, 2013 Objective: This article reports findings from a UK-based study which explored the phenomenon of overseas travel for fertility treatment. The first phase of this project aimed to explore how infertility clinicians and others professionally involved in ...
Pacey, Allan +10 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The Positive Assistance of Assisted Reproductive Technology
Epilepsy CurrentsSeizure Control in Women With Epilepsy Undergoing Assisted Reproductive Technology Abdulrazaq AA, Ainsworth AJ, Britton JW, Shenoy CC, Babayev SN, Cascino GD, Smith KM. Epilepsia
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Assisted reproductive technological blunders (ARTBs) [PDF]
Journal of Medical Ethics, 2003 When things go wrong with assisted reproduction we should look at what’s best for everyone in the particular circumstances A RTBs, as we must now call them, are becoming more and more frequent. In the recent United Kingdom case (discussed in April JME 1–3) Mr and Mrs A, a “white” couple, gave birth to twins described as “black”.
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Commentary: Can Assisted Reproductive Technology (ART) Impact Singapore’s Low Fertility Rate? [PDF]
, 2013 Singapore has consistently posted below-population replacement rates for the past four decades, despite periodic ‘Dragon Year’ spikes, firmly locating it as one of the world’s least fecund societies.
Lee, Geok Ling, Blyth, Eric
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source