Results 31 to 40 of about 9,884,518 (268)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome

Journal of Nanobiotechnology, 2023
The immune system is closely associated with the pathogenesis of polycystic ovary syndrome (PCOS). Macrophages are one of the important immune cell types in the ovarian proinflammatory microenvironment, and ameliorate the inflammatory status mainly ...
Sisi Yan, Zhipeng Gao, Jinli Ding, Suming Chen, Zehao Wang, Wenyi Jin, Bing Qu, Yi Zhang, Lian Yang, Duanying Guo, Tailang Yin, Yanbing Yang, Yan Zhang, Jing Yang   +13 more
doaj   +1 more source

The Influence of the Vanishing Twin on the Perinatal Outcome of Surviving Singleton in IVF Pregnancy

Frontiers in Endocrinology, 2022
ObjectiveThe purpose of this study was to clarify the influence of the vanishing twin (VT) on the perinatal outcomes in the surviving singleton and further identify the susceptible window.Study designRetrospective cohort study.MethodsA total of 636 ...
Jiarong Li, Jiarong Li, Jiarong Li, Jiarong Li, Jiarong Li, Jiarong Li, Jingyu Li, Jingyu Li, Jingyu Li, Jingyu Li, Jingyu Li, Jingyu Li, Yiyuan Zhang, Yiyuan Zhang, Yiyuan Zhang, Yiyuan Zhang, Yiyuan Zhang, Yiyuan Zhang, Kuona Hu, Kuona Hu, Kuona Hu, Kuona Hu, Kuona Hu, Kuona Hu, Na Chen, Na Chen, Na Chen, Na Chen, Na Chen, Na Chen, Jie Gao, Jie Gao, Jie Gao, Jie Gao, Jie Gao, Jie Gao, Jingmei Hu, Jingmei Hu, Jingmei Hu, Jingmei Hu, Jingmei Hu, Jingmei Hu, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Linlin Cui, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen   +55 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Roles of Mitochondrial SIRT4 in Cellular Metabolism

Frontiers in Endocrinology, 2019
Sirtuins comprise a family of nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacylases that regulate the life span, aging, and metabolism. Seven sirtuin family members (SIRT1-7) have been identified in mammals, including humans.
Zheying Min, Zheying Min, Jiangman Gao, Yang Yu   +3 more
doaj   +1 more source

Non-Coding RNAs Regulate Placental Trophoblast Function and Participate in Recurrent Abortion

Frontiers in Pharmacology, 2021
Recurrent spontaneous abortion (RSA) is a serious pregnancy complication with an increasing clinical incidence. The various causes of recurrent abortion are complicated.
Xin Chen, Duan-Ying Guo, Tai-Lang Yin, Jing Yang   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Book Review: Magical Progeny, Model Technology: A Hindu Bioethics of Assisted Reproductive Technology [PDF]

, 2007
A review of Magical Progeny, Model Technology: A Hindu Bioethics of Assisted Reproductive Technology by Swasti ...
Coward, Harold, Harold Coward
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source