Results 21 to 30 of about 9,404,323 (308)

New insights into the genic and metabolic characteristics of induced pluripotent stem cells from polycystic ovary syndrome women

open access: yesStem Cell Research & Therapy, 2018
Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that affects female fertility. However, with the lack of a corresponding research model, the pathology mechanism of PCOS is poorly understood.
Zheying Min   +7 more
doaj   +1 more source

Research Advances in Gametogenesis and Embryogenesis Using Pluripotent Stem Cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
The previous studies of human gametogenesis and embryogenesis have left many unanswered questions, which hinders the understanding of the physiology of these two vital processes and the development of diagnosis and treatment strategies for related ...
Yuxin Luo, Yang Yu, Yang Yu
doaj   +1 more source

Effectiveness, safety, and practicality of intramuscular progesterone in restoring pregnancy outcomes during frozen embryo transfers

open access: yesFrontiers in Endocrinology
ObjectiveTo evaluate whether progesterone (P4) supplementation in patients with low serum progesterone levels after normal luteal phase support (LPS) improves pregnancy outcomes in women undergoing frozen embryo transfer (FET).MethodsA retrospective ...
Chien Ngoc Nguyen   +18 more
doaj   +1 more source

Dual role for the unfolded protein response in the ovary: adaption and apoptosis

open access: yesProtein & Cell, 2016
The endoplasmic reticulum (ER) is the principal organelle responsible for several specific cellular functions including synthesis and folding of secretory or membrane proteins, lipid metabolism, and Ca2+ storage.
Ning Huang, Yang Yu, Jie Qiao
doaj   +1 more source

C/EBP-β and SIRT1 regulate IL-18 expression in the proliferative phase endometria of polycystic ovary syndrome patients

open access: yesGynecology and Obstetrics Clinical Medicine, 2021
Background: Previous studies have shown that polycystic ovary syndrome (PCOS) patients suffer from low-grade chronic inflammation. Furthermore, our previous studies have confirmed that IL-18 is highly expressed in the serum and endometria of PCOS ...
Xiaoyu Long   +5 more
doaj   +1 more source

Reproductive tract microbiome in assisted reproductive technologies [PDF]

open access: yesFertility and Sterility, 2015
The human microbiome has gained much attention recently for its role in health and disease. This interest has come as we have begun to scratch the surface of the complexity of what has been deemed to be our "second genome" through initiatives such as the Human Microbiome Project.
Jason M, Franasiak, Richard T, Scott
openaire   +2 more sources

Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment

open access: yesMedicina, 2019
Background and objective: Endometrial angiogenesis is a prerequisite for successful pregnancy. Optical coherence tomography (OCT) is a non-invasive physically optical imaging technique widely used in ophthalmology and cardiology.
Tracy Sze Man Law   +7 more
doaj   +1 more source

Below population replacement fertility rates: Can assisted reproductive technology (ART) help reverse the trend? [PDF]

open access: yes, 2013
Objective: This paper considers the potential contribution that assisted reproductive technology (ART) may make to population replenishment in countries that have experienced extended periods of below-population-replacement Total Fertility Rates (TFR ...
Blyth, Eric
core   +1 more source

Bioethics of Assisted Reproductive Technology [PDF]

open access: yes, 2020
There is no doubt that for a couple who are having difficulties in conceiving, having a child is an objective good. However, it is also indisputable that assisted reproduction techniques raise clear ethical issues. In order to begin this bioethical
Tudela Cuenca, Julio   +3 more
core   +2 more sources

A Novel Splicing Mutation in the FBN2 Gene in a Family With Congenital Contractural Arachnodactyly

open access: yesFrontiers in Genetics, 2020
Congenital contractural arachnodactyly (CCA) is an extremely rare monogenic disorder in humans, and the prevalence of CCA is estimated to be less than 1 in 10,000 worldwide.
Peiwen Xu   +33 more
doaj   +1 more source

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