Results 81 to 90 of about 318,953 (318)

Sperm selection strategies and their impact on assisted reproductive technology outcomes

Andrologia, 2020
The application of assisted reproductive technologies (ART) has revolutionised the treatment of human infertility, giving hope to the patients previously considered incapable of establishing pregnancy.
S. Pinto, D. Carrageta, M. Alves, A. Rocha, A. Agarwal, A. Barros, P. Oliveira   +6 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Access to infertility care services towards Universal Health Coverage is a right and not an option

BMC Health Services Research, 2022
Background In Morocco, the national health plan 2025 was developed to promote Sexual and Reproductive Health (SRH) services for all. The principal aim was to achieve the Universal Health Coverage of SRH by 2030.
Rachid Bezad, Sanae El Omrani, Amal Benbella, Bouchra Assarag   +3 more
doaj   +1 more source

Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, 2020
Since 2007, the Japan Society of Obstetrics and Gynecology (JSOG) has collected cycle‐based data for assisted reproductive technology (ART) in an online registry. Here, we present the characteristics and treatment outcomes of ART cycles registered during
O. Ishihara, S. Jwa, A. Kuwahara, Y. Katagiri, Y. Kuwabara, T. Hamatani, M. Harada, Y. Osuga   +7 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The effects of daily meteorological perturbation on pregnancy outcome: follow-up of a cohort of young women undergoing IVF treatment

Environmental Health, 2019
Background Human reproduction follows a seasonal pattern with respect to spontaneous conception, a phenomenon wherein the effect of meteorological fluctuations might not be unique.
Mingpeng Zhao, Haoyang Zhang, Tarah H. B. Waters, Jacqueline Pui Wah Chung, Tin Chiu Li, David Yiu Leung Chan   +5 more
doaj   +1 more source

Associations of Assisted Reproductive Technology and Twin Pregnancy With Risk of Congenital Heart Defects

JAMA pediatrics, 2020
This cohort study assesses the extent of association of assisted reproductive technology with congenital heart defects independent of its known association with twin pregnancies.
S. Wen, Q. Miao, M. Taljaard, J. Lougheed, L. Gaudet, M. Davies, A. Lanes, A. Leader, D. Corsi, A. Sprague, M. Walker   +10 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Roles of vitamin D in reproductive systems and assisted reproductive technology.

Endocrinology, 2020
Vitamin D, an essential steroid hormone in the human body, plays important roles in not only regulation of calcium and phosphorus metabolism, but also various physiological processes, such as cell differentiation and apoptosis, inflammation, and insulin ...
Yilu Chen, X. Zhi
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source