Results 81 to 90 of about 299,829 (366)

Assisted reproductive technology in Japan: A summary report for 2018 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology

open access: yesReproductive Medicine and Biology, 2020
Since 2007, the Japan Society of Obstetrics and Gynecology (JSOG) has collected cycle‐based data for assisted reproductive technology (ART) in an online registry. Here, we present the characteristics and treatment outcomes of ART cycles registered during
O. Ishihara   +7 more
semanticscholar   +1 more source

Effect of SARS-CoV-2 infection on human embryonic development and clinical outcomes: a retrospective cohort study

open access: yesBMC Pregnancy and Childbirth
Objective To investigate the effect of SARS-CoV-2 infection on embryonic development and clinical outcomes. Methods This retrospective analysis included 538 couples in December 2022.
Li Tian, Yiting Sun, Miaomiao Jia
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The effect of sperm DNA fragmentation index on assisted reproductive technology outcomes and its relationship with semen parameters and lifestyle.

open access: yesTranslational Andrology and Urology, 2019
Background The sperm DNA fragmentation index (DFI) is widely regarded as a key measure for assessing male fertility, but the predictive value of the DFI for outcomes of assisted reproductive technology (ART) remains under debate. In this study, we used a
Hong-yi Yang   +4 more
semanticscholar   +1 more source

Associations of Assisted Reproductive Technology and Twin Pregnancy With Risk of Congenital Heart Defects

open access: yesJAMA pediatrics, 2020
This cohort study assesses the extent of association of assisted reproductive technology with congenital heart defects independent of its known association with twin pregnancies.
S. Wen   +10 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Imprinting and assisted reproductive technology [PDF]

open access: yesHuman Molecular Genetics, 2005
In the past 25 years, the frequency of assisted reproductive technology (ART) births has increased rapidly to account for 1-2% of all births in many developed countries. ART procedures such as in vitro fertilization and intracytoplasmic sperm injection are generally considered to be safe, but recent studies suggest a small excess of birth defects and ...
openaire   +3 more sources

Growth Hormone Promotes in vitro Maturation of Human Oocytes

open access: yesFrontiers in Endocrinology, 2019
Increasing the success rate of in vitro maturation (IVM) for human oocytes has a major clinical significance. Previous studies have shown that growth hormone (GH) added into IVM medium could promote IVM of oocytes from non-human beings.
Yue Li   +23 more
doaj   +1 more source

The influence of timing of oocytes retrieval and embryo transfer on the IVF-ET outcomes in patients having bilateral salpingectomy due to bilateral hydrosalpinx

open access: yesFrontiers in Surgery, 2023
ObjectiveThe objective of the study was to investigate whether the sequence of oocyte retrieval and salpingectomy for hydrosalpinx affects pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET) patients.Study DesignThere were 1,610 ...
He Yilei   +35 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

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