Results 91 to 100 of about 9,964 (250)

Correction to: Musculoskeletal impairment among Syrian refugees living in Sultanbeyli, Turkey: prevalence, cause, diagnosis and need for related services and assistive products. [PDF]

Confl Health, 2021
Boggs D, Atijosan-Ayodele O, Yonso H, Scherer N, O'Fallon T, Deniz G, Volkan S, Örücü A, Pivato I, Beck AH, Akıncı İ, Kuper H, Foster A, Patterson A, Polack S.   +14 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Translation of the Rapid Assistive Technology Assessment Tool and Assessing Its Face Validity [PDF]

Journal of Rehabilitation
Objective The global demand for assistive technology (AT) is extensive, with over 2.5 billion people requiring one or more assistive devices. This number is expected to increase to 3.5 billion by 2050.
Hossein Gerivani, Amirhossein Takian, Haniye Sadat Sajadi, Marzieh Shirazikhah, Mohammad Taghi Joghataei   +4 more
doaj  

Musculoskeletal impairment among Syrian refugees living in Sultanbeyli, Turkey: prevalence, cause, diagnosis and need for related services and assistive products. [PDF]

Confl Health, 2021
Boggs D, Atijosan-Ayodele O, Yonso H, Scherer N, O'Fallon T, Deniz G, Volkan S, Örücü A, Pivato I, Beck AH, Akıncı İ, Kuper H, Foster A, Patterson A, Polack S.   +14 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

User satisfaction and dissatisfaction with assistive technology devices and services in India

Scientific Reports
User satisfaction with Assistive Technology (AT) is one of the crucial factors in the success of any AT service. The current study aimed to estimate satisfaction with AT and the reasons for dissatisfaction and unsuitability among persons with functional ...
Suraj Singh Senjam, Souvik Manna, Jeewan Singh Titiyal, Anil Kumar, Jugal Kishore   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Theories, models and frameworks to understand barriers to the provision of mobility-assistive technologies: a scoping review

BMJ Open
Objectives There is strong evidence that mobility-assistive technologies improve occupational performance, social participation, educational and employment access and overall quality of life in people with disabilities.
Daniel Hind, Becky Field, Simon Rushton, Asma Aldawood   +3 more
doaj   +1 more source