Results 121 to 130 of about 1,545,557 (316)
Nature Communications, 2016 Glioblastomas have distorted epigenomes. Here, the authors compare the genome-wide profiles of 5-methylcytosine and 5- hydroxymethylcytosine in glioblastoma and prefrontal cortex tissue reporting a correlation between these profiles and patients ...
Kevin C. Johnson +5 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Simulation of associative learning with the replaced elements model [PDF]
Behavior Research Methods, 2007 Associative learning theories can be categorized according to whether they treat the representation of stimulus compounds in an elemental or a configural manner. Since it is clear that a simple elemental approach to stimulus representation is inadequate, there have been several attempts to produce more elaborate elemental models.
openaire +4 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties. [PDF]
, 2012 A methicillin-resistant Staphylococcus aureus (MRSA) clone known as ST398 has emerged as a major cause of acute infections in individuals who have close contact with livestock.
Hirschberg, DL +13 more
core +1 more source
What elements of the patient–pharmacist relationship are associated with patient satisfaction?
Patient Preference and Adherence, 2012 Suliman A AlGhurair, Scot H Simpson, Lisa M GuirguisDepartment of Pharmacy Practice, University of Alberta, Edmonton, CanadaBackground: Optimal medication management requires an effective relationship between the patient and health care professional.
AlGhurair SA, Simpson SH, Guirguis LM
doaj
DNA on the move: mechanisms, functions and applications of transposable elements
FEBS Open BioTransposons are mobile genetic elements that have invaded all domains of life by moving between and within their host genomes. Due to their mobility (or transposition), transposons facilitate horizontal gene transfer in bacteria and foster the evolution ...
Michael Schmitz, Irma Querques
doaj +1 more source
EarthGlaciers are significant sources of fresh water on planet Earth. The Hindukush–Karakoram–Himalayan (HKH) glaciers provide the water supply to more than half of the human population of the globe, for agricultural activities, biodiversity survival, and ...
Kashmala Jadoon +7 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Leaders' opinions of elements in establishing and sustaining a high performance people centered culture [PDF]
, 2000 Plan BThe purpose of this study is to conduct a descriptive study that will determine leaders’ opinions of elements in establishing and sustaining a high performing people centered culture. This is Phase I of a two-part study. Phase II of this study will
Stump, Emily S.
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