Results 51 to 60 of about 12,008,060 (261)
BMC BiologyCRISPR are adaptive immunity systems that protect bacteria and archaea from viruses and other mobile genetic elements (MGE) via an RNA-guided interference mechanism.
Eugene V. Koonin, Kira S. Makarova
doaj +1 more source
Journal of XenobioticsZirconium (Zr), hafnium (Hf) and tellurium (Te) are environmentally and technologically relevant elements whose occurrence in wild macrofungi remains insufficiently characterised.
Antonio Peña-Fernández +3 more
doaj +1 more source
Two Retrotransposon Elements in Intron of Porcine BMPR1B Is Associated with Phenotypic Variation
Life, 2022 It has been established that through binding to bone morphogenetic proteins (BMPs), bone morphogenetic protein receptor I B (BMPR1B) can mediate transforming growth factor β (TGF-β) signal transduction, and is involved in the regulation of several ...
Chenglin Chi +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Endothelial gene regulatory elements associated with cardiopharyngeal lineage differentiation
Communications BiologyEndothelial cells (EC) differentiate from multiple sources, including the cardiopharyngeal mesoderm, which gives rise also to cardiac and branchiomeric muscles.
Ilaria Aurigemma +9 more
doaj +1 more source
Genomic variation associated with carcinoma showing thymus‐like elements (CASTLE) in thyroid gland
Laryngoscope Investigative Otolaryngology, 2022 Background Carcinoma showing thymus‐like elements (CASTLE) is a rare kind of malignant tumor of thyroid gland. The genetic mutation characteristics of CASTLE are not clear.
Lin Jiang, Wei‐Hui Zheng, Chao Chen
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Plasmids, prophages, and defense systems are depleted from plant microbiota genomes
Genome BiologyPlant-associated bacteria significantly impact plant growth and health. Understanding how bacterial genomes adapt to plants can provide insights into their growth promotion and virulence functions.
Avi Bograd +2 more
doaj +1 more source