Results 71 to 80 of about 1,545,557 (316)

CRISPR in mobile genetic elements: counter-defense, inter-element competition and RNA-guided transposition

BMC Biology
CRISPR are adaptive immunity systems that protect bacteria and archaea from viruses and other mobile genetic elements (MGE) via an RNA-guided interference mechanism.
Eugene V. Koonin, Kira S. Makarova
doaj   +1 more source

Genomic variation associated with carcinoma showing thymus‐like elements (CASTLE) in thyroid gland

Laryngoscope Investigative Otolaryngology, 2022
Background Carcinoma showing thymus‐like elements (CASTLE) is a rare kind of malignant tumor of thyroid gland. The genetic mutation characteristics of CASTLE are not clear.
Lin Jiang, Wei‐Hui Zheng, Chao Chen
doaj   +1 more source

Associate elements in commutative rings

Rocky Mountain Journal of Mathematics, 2014
This paper deals with several kinds of associateness of elements in commutative rings, and the connections between them. For example, in this paper, two elements \(a\) and \(b\) in a commutative ring \(R\) are called \textit{associates} if \(aR=bR\). The ring \(R\) is \textit{strongly associate} if for two associate elements \(a\) and \(b\), we have ...
Anderson, D.D., Chun, Sangmin
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

In silico identification and characterization of AGO, DCL and RDR gene families and their associated regulatory elements in sweet orange (Citrus sinensis L.). [PDF]

, 2020
RNA interference (RNAi) plays key roles in post-transcriptional and chromatin modification levels as well as regulates various eukaryotic gene expressions which are involved in stress responses, development and maintenance of genome integrity during ...
Ahmed, Fee Faysal, Akond, Zobaer, Hafizur Rahman, Rahman, Hafizur, Md Nurul Haque Mollah, Moni, Mohammad Ali, Fee Faysal Ahmed, Md Asif Ahsan, Md Parvez Mosharaf, Md Mazharul Islam, Mohammad Ali Moni, Zobaer Akond, Mosharaf, Md. Parvez, Ahsan, Md. Asif, Mollah, Md. Nurul Haque, Islam, Md. Mazharul   +15 more
core   +1 more source

Endothelial gene regulatory elements associated with cardiopharyngeal lineage differentiation

Communications Biology
Endothelial cells (EC) differentiate from multiple sources, including the cardiopharyngeal mesoderm, which gives rise also to cardiac and branchiomeric muscles.
Ilaria Aurigemma, Olga Lanzetta, Andrea Cirino, Sara Allegretti, Gabriella Lania, Rosa Ferrentino, Varsha Poondi Krishnan, Claudia Angelini, Elizabeth Illingworth, Antonio Baldini   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Describing and characterizing the WAK/WAKL gene family across plant species: a systematic review

Frontiers in Plant Science
Wall-associated kinases (WAKs) and WAK-likes (WAKLs) are transmembrane pectin receptors which have seen rising interest in recent years due to their roles in stress responses and developmental pathways. Consequently, the genes encoding these proteins are
Aaron Harvey, Noëlani van den Berg, Velushka Swart   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source