Results 121 to 130 of about 9,625,586 (342)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

The Medico-Psychological Association of Great Britain and Ireland [PDF]

open access: bronze, 1917
David Thomson   +56 more
openalex   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Influence of Professional Associations on Regional Policy in Education: International Experience

open access: yesJournal of Danubian Studies and Research, 2013
On the basis of the organizational development analisys, as well as literature review and author’s participation in the European and American professional associations the main ideas to establish the ratio between regional government bodies and non ...
Svetlana Tezikova
doaj  

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.

open access: yesEuropean Heart Journal-Cardiovascular Imaging, 2016
S. Nagueh   +13 more
semanticscholar   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Positive Association Between the Cardiometabolic Index and the Risk of Male Biochemical Androgen Deficiency in Adults

open access: yesKaohsiung Journal of Medical Sciences
Metabolic disorders are associated with testosterone deficiency, and the cardiometabolic index (CMI) is a recently identified metabolic indicator.
Shuai‐Shuai Mao   +2 more
doaj   +1 more source

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