Results 211 to 220 of about 323,732 (380)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Introduction to Asterisk with Trixbox

This presentation, made available by the National Convergence Technology Center (CTC), provides an introduction to Asterisk with TrixBox.
DâIngianni, Vincente
core  

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Rapgef1 paralog-mediated regulation of Wnt/β-catenin signaling orchestrates early embryo tissue patterning and morphogenesis. [PDF]

Cell Commun Signal
Prasad T, Iyer S, D'silva S, Mathew RJ, Sowpati DT, Radha V, Kumar M.   +6 more
europepmc   +1 more source

Tabulated summary of T-staging of laryngeal carcinoma in each laryngeal subdivision. Asterisks (*) means presence of any one feature.

Adeena Khan (17304816), Waleed M. S. Fawzy (17304819), Syed Shahid Habib (6336014), Mamoona Sultan (17304825), Manal Bukhari (22170025)   +4 more
openalex   +1 more source

Bliver vi smartere af smart teknologi?:Smartphones og tablets invaderer vores hverdag – og vores hjerter. Asterisk har mødt en af teknologifilosofiens store tænkere, den amerikanske professor Don Ihde, til et interview om mekanisk kærlighed, og hvad de nye digitale touch-teknologier vil bringe med sig. [PDF]

, 2012
Robin Engelhardt
openalex  

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

The Relationship Between Magnetic Resonance Diffusion Tensor Imaging Parameters and Muscle Dysfunction in Patients with Osteoporosis: A Cross-Sectional Retrospective Study. [PDF]

Int J Gen Med
Wang H, Yang Y, Cui J, Wang Y, Zhang C, Guo Z, Zheng D.   +6 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Correction: Case Report: Diagnostic challenges in VEXAS syndrome with novel ultrastructural lung findings: IgG4-RD and vasculitis as relevant differential diagnoses. [PDF]

Front Immunol
Etzel P, Lang D, Stoiber W, Obermayer A, Öberseder G, Lamprecht B.   +5 more
europepmc   +1 more source