Results 51 to 60 of about 1,665 (182)
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, Volume 38, Issue 51, 11 September 2026.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Functions and Mechanisms of Lysine Glutarylation in Eukaryotes
Frontiers in Cell and Developmental Biology, 2021 Lysine glutarylation (Kglu) is a newly discovered post-translational modification (PTM), which is considered to be reversible, dynamic, and conserved in prokaryotes and eukaryotes.
Longxiang Xie +5 more
doaj +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.Our study expands the variant spectrum of PLCZ1, enriches the clinical characteristics of PLCZ1, and provides a solid base for the genetic counseling, diagnosis, and treatment of this condition. ABSTRACT Background Variations in the PLCZ1 gene can lead to male infertility (MIM #617214), an autosomal recessive disorder characterized by failure or ...
Jinwei Yang +12 more
wiley +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
MTCA‐Net: Multi‐Task Cascade Analysis Network for Real‐Time Sperm Quality Analysis
Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.This article proposes MTCA‐Net, a multi‐task cascaded analysis network for real‐time sperm quality assessment in intracytoplasmic sperm injection. The framework integrates detection, tracking, and segmentation modules to jointly analyze sperm morphology and motility.
Jiajin Li +10 more
wiley +1 more source
, 2019 Candidate causal variants compatible with recessive inheritance of asthenospermia. Functional consequences of 126 candidate causal variants that were compatible with recessive inheritance of asthenospermia, i.e., they were homozygous for the alternate ...
Szabolcs Nagy (2231290) +20 more
core +1 more source
Deficiency of alpha-Tocopherol in Seminal Fluid as a Probable Factor in Low Fertility in Côte d’Ivoire [PDF]
, 2010 To evaluate the level of alpha-Tocopherol in seminal fluid of patients with low fertility, forty subjects with low fertility (17 with asthenospermia and 32 with oligoasthenospermia) and 21 subjects with normal sperm parameters were recruited into this ...
Gbassi, GK, Diafouka, F
core +1 more source
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Reproductive and Developmental Medicine, 2020 Objective: To investigate the relationship between the concentration of L-carnitine in semen and sperm parameters and investigate the epigenetic profile in sperm cell after L-carnitine usage. Methods: From February 2017 to February 2018, 46 semen samples
Xiao-Hui Jiang +7 more
doaj +1 more source
Inflammation and Oxidative Stress in Male Infertility: A Narrative Review
Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.ABSTRACT Background Male infertility affects 8%–15% of couples, with male factors implicated in about half of cases; many remain idiopathic despite improved diagnostics. This narrative review addresses this gap by examining chronic inflammation as an underappreciated driver of sperm dysfunction that forms a bidirectional, self‐reinforcing cycle with ...
Donya Pourbagher +5 more
wiley +1 more source