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The mechanism of oxidative stress in asthenozoospermia and antioxidant strategies: a review [PDF]
Frontiers in EndocrinologyAsthenozoospermia, a leading cause of male infertility, is closely associated with oxidative stress (OS), which reflects an imbalance between reactive oxygen species (ROS) production and antioxidant capacity. ROS originate from both endogenous sources (e.
Yonghua He
exaly +4 more sources
Asthenozoospermia and Fertility [PDF]
Minia Journal of Medical Research, 2019 Background: Asthenozoospermia is a condition associated with low or absent sperm motility in fresh ejaculate. Absolute asthenozoospermia, i.e. 100% immotile sperm, is reported in 1of 5000 men.
Hisham A. +3 more
doaj +2 more sources
Gut dysbiosis induces the development of asthenozoospermia through butanoate metabolism [PDF]
Frontiers in ImmunologyBackgroundAsthenozoospermia is a leading cause of male infertility with a rising incidence. While gut dysbiosis is implicated in metabolic disease, its role in asthenozoospermia pathogenesis remains unclear.Materials and methodsWe conducted a case ...
Yang Pan +4 more
doaj +2 more sources
Research progress on active ingredients of traditional Chinese medicine in the treatment of asthenozoospermia [PDF]
Frontiers in Reproductive HealthAsthenozoospermia, a main cause of male infertility, is characterized by diminished sperm motility and increased morphological abnormalities, presenting a major barrier to natural conception.
Hongyu Wang +5 more
doaj +2 more sources
Novel loss-of-function SPAG17 homozygous variant segregated in a family with severe asthenozoospermia: upgrading gene-disease validity to strong [PDF]
Frontiers in EndocrinologyBackgroundSevere asthenozoospermia is a significant cause of male infertility, commonly associated with genetic defects affecting sperm motility. However, the specific genetic contributors remain underexplored.ObjectiveThis study aimed to identify a ...
Li Wang +10 more
doaj +2 more sources
DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China
Asian Journal of Andrology, 2022 Idiopathic asthenozoospermia, a common factor in male infertility, is characterized by altered sperm motility function in fresh ejaculate. Although the β-defensin 126 (DEFB126) protein is associated with asthenozoospermia, DEFB126 gene polymorphisms have
Jiao-Yu He +11 more
doaj +3 more sources
Transient Complete Asthenozoospermia
Journal of Human Reproductive SciencesLimited research exists on the mechanisms underlying asthenozoospermia associated with acquired ciliary dyskinesia. Primary ciliary dyskinesia links respiratory pathology with infertility and provides a basis for a potential mechanism.
Artenisa Kulla +2 more
doaj +3 more sources
Frontiers in EndocrinologyBackgroundAsthenozoospermia, a type of male infertility, is primarily caused by dysfunctional sperm mitochondria. Despite previous bioinformatics analysis identifying potential key lncRNAs, miRNAs, hub genes, and pathways associated with asthenospermia ...
Xiaoyan Chen, , Jiajia Hu
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Sperm metabolomic signatures of asthenozoospermia and teratozoospermia in Chinese reproductive-age men [PDF]
Scientific ReportsAsthenozoospermia and teratozoospermia are common causes of male infertility. Despite their prevalence, the underlying metabolic mechanisms remain poorly understood.
Youzhu Li +13 more
doaj +2 more sources
Experimental and Molecular Pathology, 2020 Long non-coding RNAs (lncRNAs) have a particular expression in the testicular tissue and exhibit a regulatory function on the reproduction system. ANO1-AS2 (linc02584), as an lncRNA is located near the anoctamin1 (ANO1) gene. ANO1 is an important component of the transmembrane system exhibiting expression modifications in the idiopathic infertile men ...
Mohammadreza Saberiyan +2 more
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