Proteomic profile of human spermatozoa in healthy and asthenozoospermic individuals
Reproductive Biology and Endocrinology, 2018 Asthenozoospermia is considered as a common cause of male infertility and characterized by reduced sperm motility. However, the molecular mechanism that impairs sperm motility remains unknown in most cases.
Xiaodan Cao +6 more
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Біологічні студії, 2022 Background. Analysis of the causes of infertility revealed an increase in the proportion of male factors over the past 20 years by an average of 10–12 %.
A. V. Tarnovska, A. B. Heneha
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Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]
, 2018 Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A. +8 more
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Adnexal Gland Secretion Markers in Unexplained Asthenozoospermia [PDF]
Archives of Andrology, 1994 Prostatic acid phosphatase, prostate-specific antigen, and zinc as markers of prostate, and fructose as marker of seminal vesicles were investigated in the seminal plasma of 35 idiopathic asthenozoospermic and 20 normal subjects to evaluate their relationship with sperm motility.
Carpino A +6 more
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Acta Medica Martiniana, 2022 The role of thyroid function on sperm quality has not been well studied from a pathological aspect. This study aimed to report the degree of association between the status of thyroid hormones, sperm quality and aetiology in infertile men compared to ...
Venkateswara Rao M. +3 more
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Essential role of CFTR in PKA-dependent phosphorylation, alkalinization, and hyperpolarization during human dperm capacitation [PDF]
, 2017 Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation.
Austin +63 more
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Current Issues in Molecular Biology, 2022 Zinc (in the form of Zn2+) is necessary for male fertility. Both Zn2+ quantity and its localisation have been detected in seminal plasma and ejaculated spermatozoa, suggesting its active uptake via zinc import transporters (ZIPs).
Isidora Protic +4 more
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Proteomic Landscape of Human Sperm in Patients with Different Spermatogenic Impairments
Cells, 2023 Although the proteome of sperm has been characterized, there is still a lack of high-throughput studies on dysregulated proteins in sperm from subfertile men, with only a few studies on the sperm proteome in asthenozoospermic and oligoasthenozoospermic ...
Lea Simone Becker +6 more
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Human sperm ion channel (dys)function:implications for fertilization [PDF]
, 2019 BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R. +3 more
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Linggui Yangyuan paste for patients with male infertility: a study protocol for a multicenter, double-blind, double-dummy, randomized controlled trial [PDF]
Journal of Men's Health, 2023 Male infertility affects millions of men worldwide and is increasing in prevalence, with asthenozoospermia (AS) and oligoasthenozoospermia (OA) being the most frequent causes, and current treatments are limited.
Sheng-jing Liu +7 more
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