Results 21 to 30 of about 3,927 (181)

Deficiency in AK9 causes asthenozoospermia and male infertility by destabilising sperm nucleotide homeostasisResearch in context

EBioMedicine, 2023
Summary: Background: Asthenozoospermia is the primary cause of male infertility; however, its genetic aetiology remains poorly understood. Adenylate kinase 9 (AK9) is highly expressed in the testes of humans and mice and encodes a type of adenosine ...
Yanwei Sha, Wensheng Liu, Shu Li, Ludmila V. Osadchuk, Yongjie Chen, Hua Nie, Shuai Gao, Linna Xie, Weibing Qin, Huiliang Zhou, Lin Li   +10 more
doaj   +1 more source

Melatonin ameliorates cisplatin-induced asthenozoospermia via reducing oxidative stress [PDF]

Journal of Men's Health, 2021
Background and objective: Cisplatin is an alkylating agent that has become a first-line therapy for some tumors. However, overproduction of reactive oxygen species (ROS) by cisplatin can cause male infertility, which can affect patients’ quality of ...
Yunpeng Shao, Qiao Zhou, Jun Xue, Baixin Shen, Juan Ji, Zhongqing Wei   +5 more
doaj   +1 more source

Colony-stimulating factor-1 as a potential therapeutic target in asthenozoospermia. [PDF]

Reprod Biol Endocrinol
Wang Y, Zhou Q, Huang C, Li X, Liu H, Sun Z, Han B.   +6 more
europepmc   +3 more sources

SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis. [PDF]

Mol Med Rep
Xing H, Chen S, Wang M, Zheng T, Yang B.
europepmc   +3 more sources

Biometric analysis spermograms of men of different age groups in normal and pathology in Lviv region, Ukraine

Біологічні студії, 2022
Background. Analysis of the causes of infertility revealed an increase in the proportion of male factors over the past 20 years by an average of 10–12 %.
A. V. Tarnovska, A. B. Heneha
doaj   +1 more source

Nutraceutical management of male infertility-towards new generation therapeutics

Journal of Ideas in Health, 2021
Infertility is one of the most significant public health-related concerns globally. Both male and female factors can cause it. Male factors include poor sperm quality, idiopathic oligospermia, asthenozoospermia, and isolated asthenozoospermia.
Olabode Ekerin, Calistus Okechukwu K.
doaj   +1 more source

Determining the effect of seminal plasma supplementation on sperm motility in males with asthenozoospermia: a systematic review protocol. [PDF]

BMJ Open
Willathgamuwa ND, Nammunige MK, Thennakoon TMHP, Nissanka NMTA, Withanage Dona MD, Rodrigo NS, Logenthiran PV.   +6 more
europepmc   +3 more sources

Proteomic profile of human spermatozoa in healthy and asthenozoospermic individuals

Reproductive Biology and Endocrinology, 2018
Asthenozoospermia is considered as a common cause of male infertility and characterized by reduced sperm motility. However, the molecular mechanism that impairs sperm motility remains unknown in most cases.
Xiaodan Cao, Yun Cui, Xiaoxia Zhang, Jiangtao Lou, Jun Zhou, Huafeng Bei, Renxiong Wei   +6 more
doaj   +1 more source

Decreased piRNAs in Infertile Semen Are Related to Downregulation of Sperm MitoPLD Expression

Frontiers in Endocrinology, 2021
Currently, the molecular mechanisms underlining male infertility are still poorly understood. Our previous study has demonstrated that PIWI-interacting RNAs (piRNAs) are downregulated in seminal plasma of infertile patients and can serve as molecular ...
Yeting Hong, Yanqian Wu, Jianbin Zhang, Chong Yu, Lu Shen, Hanxiao Chen, Linjie Chen, Xue Zhou, Fang Gao   +8 more
doaj   +1 more source

A correlative interaction between thyroid dysfunction and semen parameters in male infertility: A prospective case control study

Acta Medica Martiniana, 2022
The role of thyroid function on sperm quality has not been well studied from a pathological aspect. This study aimed to report the degree of association between the status of thyroid hormones, sperm quality and aetiology in infertile men compared to ...
Venkateswara Rao M., Geetha Devi K. V. N., Rajarajeswari D., Ashalatha K.   +3 more
doaj   +1 more source