Results 61 to 70 of about 6,674 (223)

Discovery of a TEKTIN-t/TEKT2 Gene Variant Encoding Sperm Flagellar Protein in Japanese Males [PDF]

, 2015
ﾃｸﾁﾝは､ﾀﾞｲﾆﾝとともに精子の鞭毛や繊毛の形成に関与したﾀﾝﾊﾟｸ質である｡ﾃｸﾁﾝには､ﾋﾄにおいて少なくとも6種類の遺伝子の存在が報告されている｡ﾃｸﾁﾝ遺伝子のうち､Tektin-t/Tekt2､Tekt3､もしくは Tekt4 が欠失することによって､精子の鞭毛が機能不全を起こし､なかでも Tektin-t/Tekt2 遺伝子の欠失は､雄性不妊症になることがﾏｳｽで示されている｡男性不妊症の原因にﾃｸﾁﾝ遺伝子の機能不全が関与することが予想される｡私たちは､ﾋﾄ TETIN-t/TEKT2
Akira TSUJIMURA, Hiromitsu TANAKA, Morimasa WADA, Yasushi MIYAGAWA, 和田 守正, 宮川 康, 田中 宏光, 辻村 晃   +7 more
core   +1 more source

NMR spectroscopy of live human asthenozoospermic and normozoospermic sperm metabolism

Reproduction and Fertility, 2022
Sperm motility varies between ejaculates from different men and from individual men. We studied normozoospermic and asthenozoospermic ejaculates after density-gradient centrifugation washing (DCG, 80/40%) and compared high- (80%) and low (40%)-motility ...
Steven Reynolds, Sarah J Calvert, Stephen J Walters, Martyn N Paley, Allan A Pacey   +4 more
doaj   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

A mélyfagyasztás hatásainak vizsgálata az emberi ivarsejtekre morfológiai és funkcionális paraméterek alapján = Investigation of the effects of cryopreservation on morphological and functional parameters of human gametes [PDF]

, 2007
-35 normozoospermiás, 27 oligozoospermiás és 42 asthenozoospermiás férfi ondómintájához pentoxyphyllin-t adtunk, emelkedő koncentrációban. Meghatároztunk azt az ideális pentoxyphyllin koncentrációt, amely leginkább javította a minta motilitását a ...
Földesi, Imre, Pál, Attila, Szöllosi, János, Zádori, János, Závaczki, Zoltán   +4 more
core  

Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia

Theranostics, 2021
Rationale: Idiopathic asthenozoospermia (iAZS) is one of the major causes of male infertility and has no effective therapeutic treatment. Understanding the potential mechanisms that cause it may be helpful in seeking novel targets and treatment strategies for overcoming the problem of low sperm motility in iAZS individuals.
Jin, Zi-Run, Fang, Dong, Liu, Bo-Heng, Cai, Jie, Tang, Wen-Hao, Jiang, Hui, Xing, Guo-Gang   +6 more
openaire   +2 more sources

Use of Pentoxifylline to Improve Seminal Parameters in Dogs

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A single oral dose of pentoxifylline (10 mg/kg) administered 40 min before ejaculation significantly improved sperm concentration and progressive motility in dogs. The effect was most pronounced in oligospermic subjects, supporting pentoxifylline as a rapid, well‐tolerated adjunct therapy for canine subfertility .
Vincenzo Cicirelli, Matteo Burgio, Lorenza Frattina, Francesco Caprio, Domenico Robbe, Federica Ariu, Annalisa Rizzo   +6 more
wiley   +1 more source

Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males

, 2006
The lipid composition of the sperm membrane has been shown to exert a significant effect upon the functional quality of spermatozoa. We have studied fatty acid composition of the phospholipids in spermatozoa in asthenozoospermic and normozoospermic men ...
Abdi, K., Doosti, M., Joshaghani, H.R., Tavilani, H., Vaisiraygani, A.   +4 more
core   +1 more source

Research progress on active ingredients of traditional Chinese medicine in the treatment of asthenozoospermia

Frontiers in Reproductive Health
Asthenozoospermia, a main cause of male infertility, is characterized by diminished sperm motility and increased morphological abnormalities, presenting a major barrier to natural conception.
Hongyu Wang, Haichao Ge, Chunyan Ge, Lianwen Zheng, Lianhai Jin, Donghai Zhao   +5 more
doaj   +1 more source

Associations Between Reproductive Disorders and Specific Physical, Mental, Personality, and Social Characteristics: A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or reject the hypothesis on the origin of infecundity, which proposes that women/men with preferred characteristics, including high ...
Juan J. Tarín, Miguel Ángel García‐Pérez, Antonio Cano   +2 more
wiley   +1 more source

Smoke, alcohol and drug addiction and male fertility [PDF]

, 2018
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
DE ANGELIS, Cristina Concetta, Di Dato, Carla, Gianfrilli, Daniele, Isidori, Andrea, Menafra, Davide, Pivonello, Rosario, Pozza, Carlotta, Sansone, Andrea   +7 more
core   +1 more source