Results 61 to 70 of about 3,612 (170)
Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.Our study expands the variant spectrum of PLCZ1, enriches the clinical characteristics of PLCZ1, and provides a solid base for the genetic counseling, diagnosis, and treatment of this condition. ABSTRACT Background Variations in the PLCZ1 gene can lead to male infertility (MIM #617214), an autosomal recessive disorder characterized by failure or ...
Jinwei Yang +12 more
wiley +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Association between ODF1 gene polymorphism and idiopathic asthenozoospermia in Sichuan
四川大学学报. 自然科学版, 2020 The purpose of this research was to study the association between polymorphisms of the ODF1 gene and idiopathic asthenozoospermia in Sichuan. We analyzed the distribution of the ODF1 gene polymorphism in 106 idiopathic asthenozoospermia and 104 fertile ...
DENG Dan +3 more
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Use of Pentoxifylline to Improve Seminal Parameters in Dogs
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.A single oral dose of pentoxifylline (10 mg/kg) administered 40 min before ejaculation significantly improved sperm concentration and progressive motility in dogs. The effect was most pronounced in oligospermic subjects, supporting pentoxifylline as a rapid, well‐tolerated adjunct therapy for canine subfertility .
Vincenzo Cicirelli +6 more
wiley +1 more source
针刺研究, 2020 Objective To evaluate the clinical effect of acupuncture combined with Chinese medicine in the treatment of oligozoospermia/asthenozoospermia. Methods Randomized controlled trials(RCTs) of acupuncture combined with traditional Chinese medicine(TCM) in ...
YANG Bin +6 more
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Oxidative Stress‐Related Programmed Cell Death in Male Infertility: Focussing on Ferroptosis
Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.ABSTRACT Oxidative stress is a common occurrence in testicular cells of infertile men and is considered a significant cause of male reproductive dysfunction. The increase in reactive oxygen species (ROS) leads to impaired spermatogenesis by activating caspases and generating free radicals from mitochondria, resulting in DNA damage and cell death ...
Nafiseh Sanei‐Ataabadi +3 more
wiley +1 more source
The relationships between changes in main biochemical parameters in sperm cells of infertile men
Біологічні студії, 2019 Detection of the regularities of functions of male genital cells, playing a principal role in the reproductive realization (environmental and psychological stresses) is especially relevant.
R. V. Fafula, Z. D. Vorobets
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Ayurvedic Management of Asthenozoospermia
International Journal of Ayurveda and Pharma ResearchInfertility is a problem of global population and is defined as the inability to conceive even after one year of unprotected coitus. It affects about 10-15% couples and male factor is directly responsible in about 30-40% cases. Asthenozoospermia is a common cause of male infertility and is characterized by reduced sperm motility.
null Asha Sreedhar, null Avani Suresh CK
openaire +1 more source
Role of pyridoxine and oxidative stress in asthenozoospermia
HeliyonInfertility is a worldwide concern, and recent research indicates that vitamin B6 deficiency may play a role in male infertility, primarily by inducing hyperhomocysteinemia and oxidative stress. These processes can have a detrimental effect on semen quality, ultimately affecting male fertility.
Roba Bdeir +2 more
openaire +3 more sources
Alcohol intake and cigarette smoking: Impact of two major lifestyle factors on male fertility
Indian Journal of Pathology and Microbiology, 2010 Context: Lifestyle factors, like alcohol intake and cigarette smoking, have been reported to affect male fertility. Aims: To find out the specific impact of alcohol and smoking on semen quality of male partners of couples seeking treatment for primary
Gaur Dushyant +2 more
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