Results 51 to 60 of about 85,562 (306)

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Is gastro-oesophageal reflux a factor in exercise-induced asthma? [PDF]

, 1998
Exercise-induced bronchoconstriction (EIB) occurs in the majority of patients with asthma. The relationship between asthma and gastro-oesophageal reflux (GER) is well defined, and the reports of exertional gastro-oesophageal acid reflux in healthy ...
Fireman, Z., Konson, N., Sternberg, A., Weiner, P., Zamir, D.   +4 more
core   +10 more sources

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Regular treatment with formoterol for chronic asthma: serious adverse events [PDF]

, 2012
Epidemiological evidence has suggested a link between beta(2)-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe ...
Altman, Blauw, Cates, Cates, Cates, Cates, Ducharme, Greenstone, Higgins, Lipworth, Nelson, Ni Chroinin, Ni Chroinin, Pearce, Pearce, Salpeter, Walters, Walters   +17 more
core   +1 more source

Exercise-induced asthma: The “Silent Asthma” [PDF]

Journal of Pediatric Health Care, 1988
Exercise-induced asthma produces discomfort and anxiety and frequently limits normal activity in children. New knowledge about exercise-induced asthma can be used by nurses to identify undiagnosed children and to control the undesirable effects produced by exercise.
openaire   +2 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Exercise-induced bronchoconstriction in children: Delphi study and consensus document about definition and epidemiology, diagnostic work-up, treatment, and follow-up

Respiratory Research
Background Exercise-induced bronchoconstriction (EIB) is common in children with asthma but can be present also in children without asthma, especially athletes.
Valentina Fainardi, Roberto Grandinetti, Nicole Mussi, Arianna Rossi, Marco Masetti, Antonella Giudice, Simone Pilloni, Michela Deolmi, Greta Ramundo, Stefano Alboresi, Barbara Maria Bergamini, Andrea Bergomi, Maria Teresa Bersini, Loretta Biserna, Paolo Bottau, Elena Corinaldesi, Sara Crestani, Nicoletta De Paulis, Simone Fontijn, Battista Guidi, Francesca Lombardi, Lanfranco Loretano, Paola Gallo, Fabio Guerrera, Sandra Mari, Francesca Marotti, Angela Miniaci, Marco Parpanesi, Silvia Pastorelli, Alessandra Piccorossi, Carlotta Povesi Dascola, Lamberto Reggiani, Roberto Sacchetti, Valeria Scialpi, Francesca Vaienti, Cristina Venturelli, Lucia Vignutelli, Giampaolo Ricci, Carlo Caffarelli, Susanna Esposito, Emilia-Romagna Asthma (ERA) Study Group   +40 more
doaj   +1 more source

Physical exercise is a non-pharmacological method to manage asthma in peoples with asthma: Systematic review

Turkish Journal of Kinesiology
Asthma is a chronic inflammatory disease of the airways that affects over 250 million people worldwide and is responsible for approximately 455,000 deaths annually.
Muhabaw Zewde, Kefelegn Zenebe
doaj   +1 more source

Features of exercise induced bronchial asthma course in schoolchildren with poly morphisms in glutation-S-transferase genes [PDF]

, 2014
With respect to the principles of bioethics, on the base of allergy department of Chernivtsi Regional Children's Hospital it has been conducted a comprehensive clinical and paraclinical examination of 51 children with symptoms of exercise induced asthma ...
Bilous, T.M., Hryhola, O.G., Koloskova, O.K., Ortemenka, Ye.P.   +3 more
core  

Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran [PDF]

, 2016
Asthma is the most common chronic disease among children, and its incidences are often imminent among elementary schoolchildren. This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in ...
Bazrafshan, B., Khodadost, M., Mehravar, F., Rafiee, S.   +3 more
core   +1 more source