Results 91 to 100 of about 1,192 (153)

Integrated LC–MS Profiling, In Vitro Antioxidant Activity, and Exploratory Molecular Docking of Selected Mangifera odorata Fruit Extract Constituents with KEAP1

Borneo Journal of Pharmacy
Natural products remain important sources of antioxidant compounds, particularly among underexplored tropical fruits. This study evaluated the antioxidant potential of Kweni (Mangifera odorata) fruit extract by integrating LC–MS profiling, in vitro ...
Mashuri Mashuri, Zairin Noor, Eko Suhartono, Husna Dharma Putera, Nia Kania, Ristaniah Rose Effendy, Iskandar Iskandar   +6 more
doaj   +1 more source

Difference Analysis of Non-Volatile and Volatile Components in Kujingcha (Ilex dabieshanensis) Compared with Green Tea (Camellia sinensis)

Horticulturae
Kujingcha (KJC) is a widely consumed substitute tea due to its unique flavor quality and health benefits. However, the biochemical basis for the formation of KJC’s unique flavor quality and health benefits remain unclear.
Linlong Ma, Yanan Peng, Dan Cao, Ping Fan, Lingyi Wang, Guobiao Feng, Aimin Lei, Baisong Hu, Yijin Liu, Yanli Liu, Xiaofang Jin   +10 more
doaj   +1 more source

Astilbin attenuated pyroptosis caused by terbuthylazine-induced histone lactylation in grass carp hepatocytes

Ecotoxicology and Environmental Safety
Terbuthylazine (TER), a triazine herbicide, can trigger excessive production of reactive oxygen species (ROS) in organisms, leading to liver damage in aquatic species.
Yu Xia, Jinping Lan, Helu Wang, Han Zhang, Qingqing Cui, Yaru Xu, Lifang Jia, Caixia Wu, Zhen-Ao Zhao   +8 more
doaj   +1 more source

Astilbin downregulates CD80 and CD86 expression on activated B cells.

, 2015
Splenocytes were isolated from naive MRL/lpr mice and stimulated with LPS (1 μg/ml) in the presence of various concentrations of astilbin for 24 h. Left panel, representative histograms comparing CD80 (A) and CD86 (B) expression gated for CD19+ cells ...
Wen Liu (39804), Yang Sun (132532), Yan Shen (12156), Jian Gao (307118), Qiang Xu (71522), Xudong Wu (720962), Lele Guo (720961), Wenjie Guo (132521), Tingting Lu (310355), Qiong Luo (502140), Xuefeng Wu (106845)   +10 more
core   +1 more source

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia

International Journal of Nanomedicine
Lingzhi Lai,1 Hao Wu,1 Liang Peng,2 Zhen Zhang,3 Xinfan Wu,1 Shuo Zheng,3 Zekang Su,3 Hongxing Chu3 1Maoming People’s Hospital, Maoming, Guangdong, People’s Republic of China; 2The First People’s Hospital of Guiyang, Guiyang, Guizhou, People’s Republic ...
Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H   +7 more
doaj  

Astilbin from </em>Smilax glabra</em> Roxb. as a pro-apoptotic agent: cytotoxicity in multiple cancer cell lines and selectivity for 5637 bladder carcinoma

This study aims to evaluate the cytotoxic and pro-apoptotic effects of astilbin, derived from Smilax glabra Roxb., on multiple cancer cell lines, including 5637 (human bladder carcinoma), A549 (lung carcinoma), and HeLa (cervical adenocarcinoma), with a ...
Phuong Nguyen Thi Mai Phuong, Nga Nguyen, Bao Nguyen, Linh Nguyen, Thi Do, Dang Nguyen, Nguyen Thi Trang Huyen   +6 more
core   +1 more source

Temporal Multi-Omics Reveals Microbial and Metabolic Succession Following Astilbin Treatment in a Human Colonic Model. [PDF]

Nutrients
Wang T, Liu C, Ji J, Zhang S, Wu S, Xia B, Xia R, Qu N, Wang M, Zhang L, Ye Y.   +10 more
europepmc   +1 more source

Astilbin Protects Against Ischemic Stroke by Regulating ERK1/2/CREB/p90RSK Signaling and Ferroptosis-Related SLC7A11/ACSL4/GPX4 Axis: Insights from Network Pharmacology, Multi-Omics, and Molecular Dynamics. [PDF]

Int J Mol Sci
Jin C, Zhang Y, Li B, Cheng Z, Zheng M, Dong W, Song K, Ai Y.   +7 more
europepmc   +1 more source

Astilbin ameliorates intestinal inflammation and suppresses colorectal cancer cell proliferation by regulating NLRP3 inflammasome and nuclear factor-kappa B signaling pathway. [PDF]

Indian J Pharmacol
Han L, Deng XZ, Li Y, Hui J.
europepmc   +1 more source

Inhibition of aldose reductase by dihydroflavonols in Engelhardtia chrysolepis and effects on other enzymes

, 1996
Astilbin and neoastilbin, dihydroflavonol rhamnosides from Engelhardtia chrysolepis, showed potent inhibition of lens aldose reductase. Kinetic analysis showed astilbin exhibited uncompetitive inhibition against both dl-glyceraldehyde and NADPH.
Ohmi, I, Chou, WH, Tamura, Y, Masuda, H, Haraguchi, H, Mizutani, K, Tanaka, O   +6 more
core