Results 221 to 230 of about 226,969 (309)

Radiotherapy patterns and factors associated with pneumonitis in PACIFIC-R, a real-world study of patients with unresectable stage III non-small-cell lung cancer treated with durvalumab after chemoradiotherapy. [PDF]

Clin Transl Radiat Oncol
Filippi AR, Bar J, Christoph DC, Field JK, Fietkau R, Garassino MC, Garrido P, Haakensen VD, Kao S, McDonald F, Mornex F, Moskovitz M, Peters S, Van Den Heuvel MM, Vercauter P, Smit HJM, Solomon B, Chander P, Qiao Y, Faria J, Girard N.   +20 more
europepmc   +1 more source

Dynamics of the association between circulating levels of miRNA and pancreatic cancer risk through the years prior to pancreatic cancer diagnosis

International Journal of Cancer, EarlyView.
What's New? Early diagnosis is critical for improving pancreatic ductal adenocarcinoma prognosis, but few biomarkers currently exist. In a case–control study of 1,307 pancreatic cancer cases and matched pairs nested in prospective cohort studies, 13 miRNA–cancer associations were found to change during the blood‐draw‐to‐diagnosis time window.
Hui Cai, Veronica Wendy Setiawan, Xingyi Guo, Jie Wu, Rachael Stolzenberg‐Solomon, Yu‐Tang Gao, Jordan Berlin, Fei Ye, Qiuyin Cai, Wei Zheng, Xiao‐Ou Shu   +10 more
wiley   +1 more source

Safety and Pharmacokinetics of Nirsevimab in Japanese Infants: Primary Analysis of the Open-Label JUBILUS Trial. [PDF]

J Pediatric Infect Dis Soc
Mori M, Leach S, Learoyd M, Vijapur D, Sadow S, Wilkins D, Abe Y, Ikeda K, Kanegane H, Kano Z, Moriuchi H, Muneuchi J, Nishikomori R, Okazaki K, Takas T, Sakaguchi A, Villafana T.   +16 more
europepmc   +1 more source

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, EarlyView.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group   +19 more
wiley   +1 more source

Influence of PAI-1 gene polymorphism on the effectiveness of tezepelumab in individuals with severe asthma: a study protocol for a prospective, non-randomized, interventional, comparative trial. [PDF]

J Thorac Dis
Fukahori S, Obase Y, Fukushima C, Kosai K, Yanagihara K, Hara S, Tomari S, Tsubouchi H, Miyazaki T, Matsuo N, Matsuo A, Matsumoto N, Ide H, Tobino K, Kodaka N, Matsuse H, Arakaki W, Haranaga S, Yamamoto K, Yoshimine H, Sakakibara H, Yatera K, Tashiro H, Takahashi K, Himeji D, Mukae H.   +25 more
europepmc   +1 more source

Survival by Detection Pathway in Patients With Lung Cancer—A Nationwide Descriptive Epidemiological Study in Japan

International Journal of Cancer, EarlyView.
Lung cancer is detected primarily through screening, incidental findings, or presentation with symptoms. In Japan, the impact of detection pathway on prognosis is poorly understood, limiting evaluation of screening effectiveness. The authors of the present study analyzed Japanese National Cancer Registry data, comparing clinical characteristics and net
Ryo Koto, Atsuki Yamamoto, Ikumi Takashima, Chikako Iwao, Jung‐ho Shin, Yuko Hayashi, Hiroshi Kitagawa, Yoshiharu Horie   +7 more
wiley   +1 more source

Integrating baseline ctDNA-derived tumor metrics enhances risk stratification in HR-positive/HER2-negative advanced breast cancer: a real-world multicenter cohort study from Austria. [PDF]

ESMO Open
Dobrić N, Hasenleithner SO, Suppan C, Klocker EV, Hlauschek D, Graf R, Beichler C, Albertini C, Egle D, Liu D, Starzer AM, Bartsch R, Moser T, Rinnerthaler G, Jost PJ, Heitzer E, Dandachi N, Balic M.   +17 more
europepmc   +1 more source

Development and Release of the Munich UICC Staging Tool (MUST): Advancing UICC Staging in Real‐World Data With Insights From Pancreatic and Stomach Cancer

International Journal of Cancer, EarlyView.
Accurate cancer staging is essential for cancer research and treatment evaluation. However, real‐world data often include incomplete or inconsistent UICC staging classifications. The presented Munich UICC Staging Tool (MUST) automates UICC stage derivation from TNM classifications and tumor characteristics, incorporating novel real‐world data rules to ...
Brigitte Kühnel, Sophie Schneiderbauer, Sebastian Lange, Dirk Wilhelm, Helmut Friess, Marcus Feith, Ursula Ehmer, Florian Bassermann, Julian W. Holch, Stefan M. Munker, Jens Neumann, Jens Werner, Hubert J. Stein, Theres Fey, Ulrich Mansmann, Hana Algül, Karin Berger‐Thürmel, H. Carlo Maurer, Daniel Nasseh   +18 more
wiley   +1 more source

Digital heart failure management: Insights from the COPILOT study. [PDF]

Heart Fail Rev
Rolland JM, Øvrebotten T, Damman K, Greene SJ, Myhre PL.   +4 more
europepmc   +1 more source

Neoadjuvant Atezolizumab and Chemotherapy for Non‐Squamous Non‐Small Cell Lung Cancer: Efficacy and Safety Results of an Open‐Label, Single‐Arm, Phase II Trial

International Journal of Cancer, EarlyView.
Surgery plus chemotherapy is a well‐established treatment protocol for resectable, locally advanced non‐small cell lung cancer (NSCLC). Nonetheless, survival gains remain limited, emphasizing the need for more effective treatments. Here, the authors evaluated a novel approach using a neoadjuvant immunotherapy‐chemotherapy regimen consisting of ...
Benedikt Niedermaier, Tilmann Bochtler, Florian Eichhorn, Raffaella Griffo, Laura V. Klotz, Michael Allgäuer, Albrecht Stenzinger, Helge Bischoff, Marc A. Schneider, Petros Christopoulos, Uwe Haberkorn, Claus Peter Heussel, Inka Zoernig, Felix J. F. Herth, Michael Thomas, Alexander Rölle, Hauke Winter, Axel Benner, Dirk Jaeger, Martin E. Eichhorn   +19 more
wiley   +1 more source