Results 231 to 240 of about 226,969 (309)

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

International Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen, Vincent R. Lanting, Paul Manoukian, Marc G. Besselink, Geert Kazemier, Ignace H. J. T. de Hingh, Mike S. L. Liem, Casper H. J. van Eijck, Erwin van der Harst, Vincent E. de Meijer, Ronald M. van Dam, Martijn W. J. Stommel, Jan Koster, Michael W. T. Tanck, Arantza Fariña Sarasqueta, Joanne Verheij, Frederike Dijk, Johanna W. Wilmink, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven, for the Dutch Pancreatic Cancer Group   +20 more
wiley   +1 more source

Global advances and future directions in lung cancer care: expert consensus and strategic priorities. [PDF]

ESMO Open
Meyer ML, Peters S, Jänne PA, Mok TS, Bunn PA, Abdel Karim N, Altorki NK, Arrieta O, Bar J, Cappuzzo F, Carbone D, Dacic S, Diehn M, Dziadziuszko R, Felip E, Flores R, Florez N, Forde PM, Gainor JF, Gray JE, Gros L, Halmos B, Henschke CI, Herbst R, Heymach JV, Kelly K, Kris MG, Leighl NB, Mathias C, Marron TU, Mulshine JL, Naidoo J, Osarogiagbon R, Passaro A, Peled N, Planchard D, Politi K, Popat S, Pyenson B, Reckamp KL, Ren SH, Riely GJ, Rolfo C, Rudin CM, Sen T, Shields MD, Singh H, Skoulidis F, Solomon BJ, Stahel R, Stiles BM, Syrigos K, Yang JC, Yang PC, Wolf A, Wozniak AJ, Waqar SN, Wakelee H, Hirsch FR.   +58 more
europepmc   +1 more source

Real‐World Outcomes of Nivolumab and Ipilimumab in Metastatic Melanoma as Third Line and Beyond

International Journal of Cancer, EarlyView.
Progression after anti‐PD‐1‐based therapy is a predominant scenario in metastatic melanoma. However, real‐world data informing treatment of metastatic melanoma in later lines remains scarce. This retrospective nationwide, population‐based cohort study shows in a real‐world setting that nivolumab plus ipilimumab can induce durable responses beyond the ...
Yago Garitaonaindia, Søren Kjær Petersen, Louise M. Guldbrandt, Troels H. Borch, Christina H. Ruhlmann, Rasmus Blechingberg Friis, Adam A. Luczak, Lars Bastholt, Henrik Schmidt, Inge Marie Svane, Eva Ellebaek, Marco Donia   +11 more
wiley   +1 more source

Response to the Letter to the Editor by Zambelli et al for In Silico Lung Deposition Profiles of Three Single-Inhaler Triple Therapies in Patients With COPD Using Functional Respiratory Imaging [Response To Letter]. [PDF]

Int J Chron Obstruct Pulmon Dis
Singh D, Roche N, Wu L, Sadafi H, De Backer J, Monshi Tousi N, Marshall J.   +6 more
europepmc   +1 more source

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

International Journal of Cancer, EarlyView.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner, Henning Schäffler, Lothar Häberle, Chloë Goossens, Kerstin Pfister, Elena Leinert, Kristina Veselinovic, Sara Y. Brucker, Uwe Köhler, Georg Heinrich, Andreas Schneeweiss, Matthias W. Beckmann, Peter A. Fasching, Wolfgang Janni, Brigitte Rack, Sabine Heublein, Philipp Ziegler   +16 more
wiley   +1 more source

Pharmacodynamics of Camizestrant Treatment in Postmenopausal Women With Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Primary Breast Cancer: Results From the Randomized, Presurgical SERENA-3 Study. [PDF]

J Clin Oncol
Robertson JFR, Gogitidze T, Katashvili Z, Rocha JEB, Arkania E, Moppett I, Cheung KL, Nemsadze G, Ajimi M, Klinowska T, Lindemann JPO, Mathewson A, Morrow CJ, Nikolaou M, Scaltriti M, Sykes A, Dzagnidze G.   +16 more
europepmc   +1 more source

Phase III trial of infigratinib versus gemcitabine/cisplatin in adults with advanced cholangiocarcinoma with FGFR2 gene fusion or rearrangement: results and reflections on early termination of PROOF 301. [PDF]

ESMO Open
Abou-Alfa GK, Borbath I, Roychowdhury S, Goyal L, Lamarca A, Macarulla T, Shroff RT, Oh DY, Tamaş C, Savastano DM, van Veenhuyzen DF, Xu C, Freas E, Solanas J, Javle MM.   +14 more
europepmc   +1 more source

How does pulmonary function impact QoL in patients with locally advanced NSCLC treated with chemoradiotherapy and durvalumab? [PDF]

Acta Oncol
Sommervoll FÅ, Horndalsveen H, Sommervoll DE, Koivonen J, Halvorsen TO, Grønberg BH, Aanerud M, Cicenas S, Helbekkmo N, Ahvonen J, Silvoniemi M, Barrera G, Bjaanæs MM, Haakensen V, Öjlert Å, Oselin K, Helland Å, Madebo T.   +17 more
europepmc   +1 more source

Safety and efficacy of ravulizumab in patients with NMOSD previously treated with rituximab: A post hoc analysis of the CHAMPION-NMOSD trial. [PDF]

Mult Scler
Bennett JL, Bhattacharyya S, Zabeti A, Levy M, de Sèze J, Taney MJ, Parks B, Allen K, Akpoji U, Pittock SJ.   +9 more
europepmc   +1 more source

Multimorbidity phenotypes and associated characteristics in severe asthma: an observational study of European severe asthma registries. [PDF]

Lancet Reg Health Eur
Freeman A, Rink S, Bansal AT, Frankemölle B, Singh M, Sont JK, Bossios A, Ainsworth B, Hyland M, Chaudhuri R, Matisa D, Mihaltan F, Spanevello A, Heffler E, Adcock I, Zappa M, Canonica GW, Brusselle G, Bourdin A, Maria Luigia Costanzo GA, Horvath I, Lúðvíksdóttir D, Principe S, Kopač P, Loureiro CC, Siddiqui S, Egesten A, Kalinauskaite-Zukauske V, Dimic-Janjic S, Roberts G, Hromis S, Milenkovic B, Varkonyi-Sepp J, Goksel O, Pereira AM, Djukanovic R, Rizzi A, Caminati M, Hou R, Štajduhar A, Paróczai D, Brussino L, Heaney L, Haitchi HM, Bonini M, Bieksiene K, Damadoglu E, Yasinska V, Gemicioglu B, Grle SP, Brinke AT, Csoma Z, Kroica I, Kuna P, Dahlen B, Porsbjerg C, Hodge H, Škrgat S, Schleich F, Kurukulaaratchy RJ.   +59 more
europepmc   +1 more source