Results 31 to 40 of about 226,969 (309)

AstraZeneca COVID‐19 vaccine: A possible risk factor for ischemic stroke and cerebral venous sagittal sinus thrombosis: A case series

Clinical Case Reports, 2022
One of the most prevalent neurological impairments is cerebrovascular accident (CVA). Ischemic stroke and CVST have been linked to the AstraZeneca COVID‐19 vaccine. Three Sudanese patients developed these diseases after receiving the AstraZeneca COVID‐19
Amira Siddig, Khabab Abbasher Hussien Mohamed Ahmed, Mazin S. Hassan Haroun, Abdallah M. Abdallah, Mohamed Malekaldar, Al Hussien Abbasher, Mohammed Abbasher, Abubaker Alsedig Abbasher, Abbasher Hussien   +8 more
doaj   +1 more source

Public awareness of cancer in the Gaza-Strip: A cross-sectional study [PDF]

, 2018
Background: Cancer is one of the leading causes of death worldwide. Most deaths from cancer occurs in low- and middle- income countries, which might be explained by the delayed presentation of the cancer patient.
Abu-Nemer, K., Albarqouni, L., Alkhatib, M., Alshorbassi, N., Baraka, O., Bottcher, B., Elblbessy, M., Elshami, A., Elshami, M. S., Hana, M., Matar, G., Qandeel, A.   +11 more
core   +1 more source

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression [PDF]

, 2012
Background: Randomized, double-blind, placebo-controlled trials constitute the gold standard in clinical research when testing the efficacy of new psychopharmacological interventions in the treatment of major depression.
A Cipriani, A Cipriani, A Hrobjartsson, A Loh, Andrea Pfennig, BR Rutherford, CP Gross, DE Moerman, DL Sackett, EA Largent, Emanuel Severus, F Seemuller, FG Miller, Florian Seemüller, G Parker, GI Papakostas, H Brody, H Brody, Hans-Jürgen Möller, HJ Moller, HJ Moller, HJ Moller, HU Wittchen, HV Krell, J Odgaard-Jensen, L Colloca, L Colloca, M Sinyor, MA Posternak, ME Wechsler, Michael Bauer, Michael Berger, Michael Obermeier, Michael Riedel, R Jones, RE Drake, RW Lam, Sandra Dittmann, SB Patten, SH Kennedy, Sophia Frangou, SR Wisniewski, U Hegerl, U Hegerl   +43 more
core   +3 more sources

Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events (Review) [PDF]

, 2009
Background Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are ...
Cates, CJ, Jaeschke, R, Lasserson, TJ
core   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM, Brown-Frandsen, K, Buse, JB, Daniels, GH, Kristensen, P, LEADER Steering Committee on behalf of the LEADER Trial Investigators, Mann, JF, Marso, SP, Nauck, MA, Nissen, SE, Pocock, S, Poulter, NR, Ravn, LS, Steinberg, WM, Stockner, M, Zinman, B   +15 more
core   +1 more source

Evaluating the Side Effects of COVID-19 Vaccines Available in Al-Diwaniyah Province

Medical Journal of Babylon
Background:Vaccines are critical to reducing the viral attack by permitting the body to generate a safe immune response that defends it by preventing or limiting infection.
Meraim Attyah Kazaal, Roaa Abid Jaythoom, Noor Dakil Mahdi, Doaa Yousief Mohammed   +3 more
doaj   +1 more source

Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models

npj Breast Cancer, 2023
Combining the selective AKT inhibitor, capivasertib, and SERD, fulvestrant improved PFS in a Phase III clinical trial (CAPItello-291), treating HR+ breast cancer patients following aromatase inhibitors, with or without CDK4/6 inhibitors.
Lorna Hopcroft, Eleanor M. Wigmore, Stuart C. Williamson, Susana Ros, Cath Eberlein, Jennifer I. Moss, Jelena Urosevic, Larissa S. Carnevalli, Sara Talbot, Lauren Bradshaw, Catherine Blaker, Sreeharsha Gunda, Venetia Owenson, Scott Hoffmann, Daniel Sutton, Stewart Jones, Richard J. A. Goodwin, Brandon S. Willis, Claire Rooney, Elza C. de Bruin, Simon T. Barry   +20 more
doaj   +1 more source

Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models

Journal for ImmunoTherapy of Cancer, 2021
Background Immuno-oncology therapies are now part of the standard of care for cancer in many indications. However, durable objective responses remain limited to a subset of patients.
Robert W Wilkinson, Hormas Ghadially, Stacy Kentner, Suzanne Isabelle Sitnikova, Sophie Munnings-Tomes, Elena Galvani, Kathy Mulgrew, Chris Rands, Judit España Agustí, Tianhui Zhang, Kristina M Ilieva, Guglielmo Rosignoli, Matthew J Robinson, Tim Slidel, Simon J Dovedi   +14 more
doaj   +1 more source

AstraZeneca's compound interest [PDF]

Science-Business eXchange, 2012
The U.K.'s Medical Research Council has partnered with AstraZeneca to make the pharma's shelved compounds available to academics investigating basic disease mechanisms. A first call for proposals is in progress.
openaire   +1 more source

Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children (Review) [PDF]

, 2009
Background Traditionally inhaled treatment for asthma has been considered as preventer and reliever therapy. The combination of formoterol and budesonide in a single inhaler introduces the possibility of using a single inhaler for both prevention and ...
Adams, Balanzat, Bateman, Berggren, Bisgaard, Bisgaard, Bleecker, Bousquet, Bruce, Buhl, Buhl, Cates, Cates Christopher, D'Urzo, Greenstone, Haahtela, Haahtela, Higgins, Higgins, Ind, Jenkins, Johansson, Jonkers, Kuna, Kuna, Lasserson, Loukides, Lundborg, Ni Chroinin, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, O'Byrne, Palmqvist, Price, Price, Rabe, Rabe, Rabe, Richter, Scicchitano, Sears, Sovani, Tattersfield, Tattersfield, Vogelmeier, Vogelmeier, Vogelmeier, Walters   +50 more
core   +1 more source