The mTOR/Akt pathway is involved in regulating astrocyte growth and GLT-1 expression during cerebral ischemia-reperfusion. [PDF]
Li Q +11 more
europepmc +1 more source
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad +9 more
wiley +1 more source
Intermittent hypoxia ameliorates behavioral deficits and exerts neurorestoration in a mouse photothrombotic stroke model. [PDF]
Wu T +7 more
europepmc +1 more source
Translatome profiling of spinal cord astrocytes reveals distinct gene signatures associated with acute and chronic pain. [PDF]
Siliezar-Doyle J +4 more
europepmc +1 more source
Dual CD73/A<sub>2A</sub>R blockade modulates the neurotoxic astrocyte phenotype without disrupting core inflammatory signaling. [PDF]
Mihajlovic K +9 more
europepmc +1 more source
Modeling CLN3 Batten disease in astrocytes reveals alterations in mitochondria homeostasis, fatty acid metabolism and oxidative stress response. [PDF]
Yang M +12 more
europepmc +1 more source
Astrocyte heterogeneity in the neocortex: developmental origins, molecular diversity, and functional implications. [PDF]
Zhou J, Bocchi R.
europepmc +1 more source
The long march towards testing the adenosine receptor agonism hypothesis for human cerebroprotection: The story of the A<sub>1</sub>R/A<sub>3</sub>R receptor agonist AST-004. [PDF]
Liston TE +3 more
europepmc +1 more source
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis [PDF]
Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of the neuropil alters synaptic connectivity.
Eray Enüstün +2 more
exaly +3 more sources
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Philip Hasel and Shane Liddelow introduce astrocytes - glial cells that help to maintain the homeostasis of the central nervous system during development, normal physiology, and aging.
Philip, Hasel, Shane A, Liddelow
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