Results 211 to 220 of about 380,989 (342)

Research progress on the regulation of microglia and astrocyte functions by protein lactylation in cerebral ischemia-reperfusion injury: A review. [PDF]

Medicine (Baltimore)
Song HH, Jiang XC.
europepmc   +1 more source

Astrocytes [PDF]

Journal of Neuropathology and Experimental Neurology, 1985
openaire   +1 more source

Alcohol dependence-induced astrocyte immune activation in the nucleus accumbens

Joel G. Hashimoto, Regina A. Mangieri, Amanda J. Roberts, Turner Lime, Brett A. Davis, Lucia Carbone, Marisa Roberto, Marina Guizzetti   +7 more
openalex   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Astrocyte heterogeneity in the neocortex: developmental origins, molecular diversity, and functional implications. [PDF]

Front Cell Dev Biol
Zhou J, Bocchi R.
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Anti-Inflammatory and Antioxidant Effects of ω-3 Polyunsaturated Fatty Acids on Astrocytes and Their Implications for the Blood-Brain Barrier's Integrity and Function. [PDF]

Int J Mol Sci
Parnova R, Fock E.
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

LPS-induced inflammation differentially affects endogenous Ca²⁺ activity in mouse and human iPSC-derived astrocytes. [PDF]

Mol Med
Müller FE, Ivanov F, Studt AC, Nitzsche I, Bahr FS, Krüger AL, Labus J, Singh G, Ponimaskin EG, Lenk K, Zeug A.   +10 more
europepmc   +1 more source

Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1 [PDF]

, 2018
Cedeno, Michelle R, Dimitry, Julie, et al,, Griffin, Percy, Haspel, Jeffery A, Lananna, Brian V, McKee, Celia A, Musiek, Erik S, Nadarajah, Collin J, Sheehan, Patrick W, Tso, Chak Foon, Xiong, David D   +11 more
core   +1 more source