Results 131 to 140 of about 109,064 (360)

miR-106a-5p Inhibits the Proliferation and Migration of Astrocytoma Cells and Promotes Apoptosis by Targeting FASTK

open access: yesPLoS ONE, 2013
Astrocytomas are common malignant intracranial tumors that comprise the majority of adult primary central nervous system tumors. MicroRNAs (miRNAs) are small, non-coding RNAs (20–24 nucleotides) that post-transcriptionally modulate gene expression by ...
F. Zhi   +12 more
semanticscholar   +1 more source

Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cerebral tumors, particularly in pediatric patients, pose a significant challenge in oncology. Radiotherapy is a crucial component of the multimodal treatment approach for these tumors. Understanding the molecular basis of these tumors, particularly their response to radiotherapy, is crucial for improving treatment outcomes and patient ...
Ahana Maitra   +9 more
wiley   +1 more source

PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

open access: yesJournal of the National Cancer Institute, 2001
BACKGROUND Survival of patients with anaplastic astrocytoma is highly variable. Prognostic markers would thus be useful to identify clinical subsets of such patients.
Justin S. Smith   +11 more
semanticscholar   +1 more source

Management of Calvarial Osteoradionecrosis After Treatment of Cutaneous Malignancy: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Osteoradionecrosis (ORN) is a recognized complication of radiotherapy. However, calvarial ORN (ORNC) following treatment for cutaneous malignancies is poorly understood. Shedding light on the limited evidence to date, this study aims to summarize existing evidence and highlight the research gaps.
Siyuan Pang   +8 more
wiley   +1 more source

Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature

open access: yesCase Reports in Pathology, 2020
Pilocytic astrocytoma is a low-grade glial neoplasm of the central nervous system (CNS) that tends to occur in the pediatric population and less commonly presents in adults.
Siobhan S. Pattwell   +5 more
doaj   +1 more source

Three and Four Courses of Radiation for Children with Recurrent Diffuse Intrinsic Pontine Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Re‐irradiation (RT2) for children with diffuse intrinsic pontine glioma (DIPG) is increasingly used upon recurrence; however, limited data are available for evaluating additional courses of radiotherapy (RT) for DIPG. The purpose of this case series was to report our institutional experience in treating patients with recurrent DIPG ...
Nisha Shariff   +3 more
wiley   +1 more source

Procarbazine, CCNU and vincristine (PCV) versus temozolomide chemotherapy for patients with low-grade glioma: a systematic review. [PDF]

open access: yes, 2018
Low-grade gliomas (LGG) encompass a heterogeneous group of tumors that are clinically, histologically and molecularly diverse. Treatment decisions for patients with LGG are directed toward improving upon the natural history while limiting treatment ...
Das, Sunit   +4 more
core   +1 more source

Long‐Term Projections of Childhood Cancer Incidence and Prevalence in Ontario, Canada Until 2040

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The prevalence of childhood cancer continues to rise due to increases in cancer incidence and advances in treatment, leading to better survival. We generated epidemiologic projections for childhood cancer, by cancer type, in Ontario, Canada, until 2040.
Alexandra Moskalewicz   +3 more
wiley   +1 more source

Malignant Rhabdoid Tumors of Cranial Nerves—A Clinically Distinct Group With Characteristic Neuroradiological, Histopathological, and Molecular Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Malignant rhabdoid tumors occasionally develop along cranial nerves, but clinical, histopathological, and molecular features have not been examined in larger series. Procedure We retrospectively interrogated data from the European Rhabdoid Registry, EU‐RHAB, to identify malignant rhabdoid tumors affecting cranial nerves.
Miriam Gruhle   +15 more
wiley   +1 more source

Pilocytic Astrocytoma Presenting as an Orbital Encephalocele: A Case Report

open access: yesCase Reports in Neurology, 2015
We describe the case of a 29-year-old male who presented with new-onset seizures. He was subsequently found to have an orbital encephalocele containing a focus of pilocytic astrocytoma.
Amy Bruzek   +3 more
doaj   +1 more source

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