Results 161 to 170 of about 109,064 (360)

Role for the liver X receptor agonist 22‐ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

British Journal of Pharmacology, EarlyView.
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens, Na Zhan, Sammie C. Yam, Marcella Palumbo, Lorenzo Pontini, Frank P. J. Leijten, Leonie van Vark‐van der Zee, Gardi Voortman, Silvia Friedrichs, Albert Gerding, Maura Marinozzi, Johan W. Jonker, Folkert Kuipers, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder   +15 more
wiley   +1 more source

Grading of astrocytomas using a Quantimet 720 image-analysing computer. [PDF]

, 1978
A J Robertson, Joseph M Anderson, Russell A. Brown, W. Slidders, Jürgen Beck   +4 more
openalex   +1 more source

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

Cancer Science, EarlyView.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe, Miho Ogawa, Aya Shinozaki‐Ushiku, Shuichi Tsutsumi, Kenji Tatsuno, Hiroyuki Aburatani, Hidenori Kage, Katsutoshi Oda   +7 more
wiley   +1 more source

Recurrence of astrocytoma of optic nerve after 48 years. [PDF]

, 1976
J Mullaney, James T. Walsh, W. Robert Lee, J. H. Adams   +3 more
openalex   +1 more source

Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties [PDF]

, 1987
Eugene O. Major, Dominick Vacante, Renee G. Traub, William T. London, John L. Sever   +4 more
openalex   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

BATseg: Boundary-aware Multiclass Spinal Cord Tumor Segmentation on 3D MRI Scans [PDF]

arXiv
Spinal cord tumors significantly contribute to neurological morbidity and mortality. Precise morphometric quantification, encompassing the size, location, and type of such tumors, holds promise for optimizing treatment planning strategies. Although recent methods have demonstrated excellent performance in medical image segmentation, they primarily ...
arxiv  

Dreaming in patients with epilepsy: a cross‐sectional cohort study

Journal of Sleep Research, EarlyView.
Dream recall frequency in patients with epilepsy is modulated by determinants shared with healthy subjects (age, nocturnal awakenings, role of the parieto‐occipital region) and by epilepsy‐related factors (seizure frequency, epileptic focus location).
Maïlis Charpentier‐Hélary, Aurélien de la Chapelle, Maxime Linard, Nathalie André‐Obadia, Sébastien Boulogne, Hélène Catenoix, Julien Jung, Sylvain Rheims, Katharina Schiller, Birgit Frauscher, Perrine Ruby, Laure Peter‐Derex   +11 more
wiley   +1 more source

Quantum-Enhanced Classification of Brain Tumors Using DNA Microarray Gene Expression Profiles [PDF]

arXiv
DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the identification of diagnostic genetic signatures.
arxiv  

Cerebrospinal metastases in malignant childhood astrocytomas [PDF]

, 1984
Raymond S. Kandt, Shlomo Shinnar, Bernard J. D’Souza, Harvey S. Singer, Moody D. Wharam, Prabodh K. Gupta   +5 more
openalex   +1 more source