Results 151 to 160 of about 48,747 (277)

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He   +17 more
wiley   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Critical Limitations in Cryogenic Laser Cooling of Solids: Symmetry‐Related Fluorescence Trapping and Condensation‐Induced Parasitic Heating

open access: yesAdvanced Science, EarlyView.
This study uncovers two overlooked bottlenecks in cryogenic laser cooling of solids: symmetry‐driven fluorescence trapping and water vapor condensation. We demonstrate that breaking sample symmetry enhances fluorescence escape, while condensation dominates parasitic heating below 135 K.
Biao Zhong   +5 more
wiley   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

open access: yesAdvanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John   +16 more
wiley   +1 more source

Observing cosmic-ray extensive air showers with a silicon imaging detector. [PDF]

open access: yesSci Rep, 2023
Kawanomoto S   +9 more
europepmc   +1 more source

High‐Conductivity Electrolytes Screened Using Fragment‐ and Composition‐Aware Deep Learning

open access: yesAdvanced Science, EarlyView.
We present a new deep learning framework that hierarchically links molecular and functional unit attributions to predict electrolyte conductivity. By integrating molecular composition, ratios, and physicochemical descriptors, it achieves accurate, interpretable predictions and large‐scale virtual screening, offering chemically meaningful insights for ...
Xiangwen Wang   +6 more
wiley   +1 more source

Exploring the extremes: The cosmic laboratory. [PDF]

open access: yesInnovation (Camb)
Huang Y, He S, Ge L, Li Z, Mao Y, Liu J.
europepmc   +1 more source

Leaky‐Integrate‐Fire Neuron via Synthetic Antiferromagnetic Coupling and Spin‐Orbit Torque

open access: yesAdvanced Science, EarlyView.
A spintronic leaky‐integrate‐and‐fire neuron is realized using Spin Orbit Torque driven domain‐wall motion for integration and synthetic antiferromagnetic coupling for the leaky process. The specialized Hall‐bar geometry enables controlled DW dynamics, achieving repeatable integration and firing events. This compact, CMOS‐compatible design highlights a
Badsha Sekh   +8 more
wiley   +1 more source

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