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International audienceBackgroundAn unmet need exists for interferon-free and ribavirin-free treatments for chronic hepatitis C virus (HCV) infection. In this study, we assessed all-oral therapy with daclatasvir (NS5A replication complex inhibitor) plus ...
Michael P Manns +2 more
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Background and Aim: Daclatasvir plus asunaprevir has demonstrated efficacy and safety in patients with chronic hepatitis C virus genotype 1b infection. This study focused on evaluating daclatasvir plus asunaprevir in interferon (+/- ribavirin)-ineligible
Mingxiang Zhang +2 more
exaly +2 more sources
Asunaprevir for hepatitis C: a safety evaluation
Expert Opinion on Drug Safety, 2015The introduction of direct-acting antiviral (DAA) agents has revolutionized the treatment of hepatitis C virus (HCV) chronic infection. Non-structural 3 protease inhibitors are currently the most numerous class of DAAs on the market.This review mainly focuses on the tolerability and safety profile of asunaprevir (ASV)-containing DAA regimens.
GENTILE, Ivan +4 more
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